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  1. The present study was conducted to learn whether the perinatal and environmental factors could influence the total and antigen-specific IgE levels in umbilical cord blood. Retrospective data were obtained from...

    Authors: AJ Sybilski, A Doboszynska and B Samolinski
    Citation: European Journal of Medical Research 2009 14(Suppl 4):233

    This article is part of a Supplement: Volume 14 Supplement 4

  2. We assessed correlations of total and specific cord-blood IgE (cIgE) levels with allergic symptoms in the first year of life. cIgE levels were determined by an immunoassay test in full-term neonates. This is a...

    Authors: AJ Sybilski, A Doboszynska and B Samolinski
    Citation: European Journal of Medical Research 2009 14(Suppl 4):227

    This article is part of a Supplement: Volume 14 Supplement 4

  3. The European Directive 98/79/EC on in vitro diagnostic medical devices (IVD) stipulates the marketing and post market surveillance of IVD in the European Economic Area. In cases of issues and field corrective act...

    Authors: R Siekmeier, J Halbauer, W Mientus and D Wetzel
    Citation: European Journal of Medical Research 2009 14(Suppl 4):216

    This article is part of a Supplement: Volume 14 Supplement 4

  4. Bronchial challenge tests by inhalation of aerosolized methacholine (MCH) are commonly used in the clinical diagnosis of airway hyperresponsiveness (AHR). While the detection of airway narrowing relies on the ...

    Authors: F Nensa, W Marek, E Marek, HJ Smith and M Kohlhäufl
    Citation: European Journal of Medical Research 2009 14(Suppl 4):170

    This article is part of a Supplement: Volume 14 Supplement 4

  5. Onconeuronal antibodies are important diagnostic tool in patients with suspicion of paraneoplastic neurological syndromes (PNS). However, their role in PNS pathophysiology and specificity for particular neurol...

    Authors: S Michalak, S Cofta, A Piatek, J Rybacka, E Wysocka and W Kozubski
    Citation: European Journal of Medical Research 2009 14(Suppl 4):156

    This article is part of a Supplement: Volume 14 Supplement 4

  6. Over the last few years, differential ion mobility spectroscopy (DMS) has become an important tool in medical research. There are attempts to find markers for specific diseases in exhaled air, using this techn...

    Authors: A Kikowatz, G Becher, S Dietze, W Steinhausser and E Beck
    Citation: European Journal of Medical Research 2009 14(Suppl 4):121

    This article is part of a Supplement: Volume 14 Supplement 4

  7. Obesity development is a complex process which can be influenced by genetic predisposition modified by environmental factors. Nowadays, the problem of overweight and obesity, including related complications, o...

    Authors: K Popko, E Górska, B Pyrzak, A Telmaszczyk-Emmel, A Wisniewska, A Majcher, M Wasik and U Demkow
    Citation: European Journal of Medical Research 2009 14(Suppl 4):59

    This article is part of a Supplement: Volume 14 Supplement 4

  8. Poor postural balance is one of the major risk factors for falling in normal pressure hydrocephalus (NPH). Postural instability in the clinic is commonly assessed based upon force platform posturography. In th...

    Authors: L Czerwosz, E Szczepek, JW Blaszczyk, B Sokolowska, K Dmitruk, K Dudzinski, J Jurkiewicz and Z Czernicki
    Citation: European Journal of Medical Research 2009 14(Suppl 4):53

    This article is part of a Supplement: Volume 14 Supplement 4

  9. The relationship between obstructive sleep apnea (OSA) and cardiovascular disease is intensively discussed. Endothelial leukocyte adhesion molecule (E-selectin) is one of factors facilitating leukocyte migrati...

    Authors: S Cofta, E Wysocka, S Michalak, T Piorunek, H Batura-Gabryel and L Torlinski
    Citation: European Journal of Medical Research 2009 14(Suppl 4):49

    This article is part of a Supplement: Volume 14 Supplement 4

  10. It had been hypothesized that the regions of prefrontal cortex which are involved in respiratory control can modulate Hering-Breuer reflexes evoked by vagal input from pulmonary stretch receptors. In the prese...

    Authors: VG Aleksandrov, VA Mercuriev, TG Ivanova, AA Tarasievich and NP Aleksandrova
    Citation: European Journal of Medical Research 2009 14(Suppl 4):1

    This article is part of a Supplement: Volume 14 Supplement 4

  11. Similar to all antiretroviral drugs, failure of raltegravirbased treatment regimens to fully supress HIV replication almost invariably results in emergence of HIV resistance to this new drug. HIV resistance to...

    Authors: François Clavel
    Citation: European Journal of Medical Research 2009 14(Suppl 3):47

    This article is part of a Supplement: Volume 14 Supplement 3

  12. Raltegravir, the first approved integrase inhibitor, has been shown to be virologically effective in Phase II and Phase III clinical trials in both treatment naïve and triple class resistant patients. It also ...

    Authors: Margaret Johnson
    Citation: European Journal of Medical Research 2009 14(Suppl 3):43

    This article is part of a Supplement: Volume 14 Supplement 3

  13. End-stage liver disease has become one of the most frequent causes of death in HIV/HCV-coinfected patients. The role of new antiretrovirals in the progression of liver fibrosis has yet to be defined. However w...

    Authors: Martin Vogel and Mark Nelson
    Citation: European Journal of Medical Research 2009 14(Suppl 3):36

    This article is part of a Supplement: Volume 14 Supplement 3

  14. Raltegravir, the first approved HIV-1 integrase inhibitor, is able to block the strand transfer step of the HIV proviral DNA integration process into the cellular host DNA. The selected dosage for the pivotal ...

    Authors: Jose M Gatell
    Citation: European Journal of Medical Research 2009 14(Suppl 3):30

    This article is part of a Supplement: Volume 14 Supplement 3

  15. Raltegravir is the first integrase inhibitor approved for the treatment of HIV infection based on the superior efficacy it showed compared to optimized backbone therapy alone in patients harboring multidrug re...

    Authors: F Cossarini, A Castagna and A Lazzarin
    Citation: European Journal of Medical Research 2009 14(Suppl 3):22

    This article is part of a Supplement: Volume 14 Supplement 3

  16. Integration of the HIV-1 viral DNA generated by reverse transcription of the RNA genome into the host cell chromosomes is a key step of viral replication, catalyzed by the viral integrase. In October 2007, the...

    Authors: Jean-François Mouscadet and Luba Tchertanov
    Citation: European Journal of Medical Research 2009 14(Suppl 3):5

    This article is part of a Supplement: Volume 14 Supplement 3

  17. The analysis of cost effectiveness in hospitals is as difficult as treating the patients properly. We are yet not able to answer the simple question of what costs are caused by a certain diagnosis and its trea...

    Authors: IM Heer, S Kahlert, S Rummel, C Kümper, W Jonat and A Strauss
    Citation: European Journal of Medical Research 2009 14:502
  18. A calcium antagonist, nifedipine, causes gingival overgrowth as a side effect. It has been confirmed that the Japanese traditional medicine, Saireito, inhibits the nifedipine-induced proliferation of gingival ...

    Authors: T Hattori, K Nakano, T Kawakami, A Tamura, T Ara and PL Wang
    Citation: European Journal of Medical Research 2009 14:497
  19. Current criteria for performing relaparotomy for suspected peritonitis are non explicit and based on non-quantitative, subjective arguments or hospital practice. The aim of this study was to determine the valu...

    Authors: FG Bader, M Schröder, P Kujath, E Muhl, H-P Bruch and C Eckmann
    Citation: European Journal of Medical Research 2009 14:491
  20. Despite having an organ confined tumor stage at the time of radical cystectomy, a certain number of bladder cancer patients will develop local or distant metastases over time. Currently there are no reliable s...

    Authors: A Karl, S Tritschler, S Hofmann, CG Stief and C Schindlbeck
    Citation: European Journal of Medical Research 2009 14:487
  21. Today, the biomechanical fundamentals of skin expansion are based on viscoelastic models of the skin. Although many studies have been conducted in vitro, analyses performed in vivo are rare. Here, we present i...

    Authors: C Marquardt, E Bölke, PA Gerber, G Kukova, M Peiper, E Rusnak, K Orth and W Fleischmann
    Citation: European Journal of Medical Research 2009 14:480
  22. German-Austrian recommendations for HIV1-therapy in pregnancy - Update 2008 Bernd Buchholz (University Medical Centre Mannheim, Pediatric Clinic), Matthias Beichert (Mannheim, Gynecology and Obstetrics Practic...

    Authors: Bernd Buchholz, Matthias Beichert, Ulrich Marcus, Thomas Grubert, Andrea Gingelmaier, Annette Haberl and Brigitte Schmied
    Citation: European Journal of Medical Research 2009 14:461
  23. Training models are required to impart surgical skills, like wound closure techniques, prior to practice in patients. In an ideal case, the tissue characteristics of the model are close to those of humans, eas...

    Authors: PN Khalil, M Siebeck, W Mutschler and K-G Kanz
    Citation: European Journal of Medical Research 2009 14:459
  24. Abnormal hypermethylation of CpG islands associated with tumor suppressor genes can lead to transcriptional silencing in neoplasia. The aim of this study was to investigate the promoter methylation and express...

    Authors: W Guo, Z Dong, Y Guo, G Kuang, Z Yang and Z Chen
    Citation: European Journal of Medical Research 2009 14:453
  25. High tibial osteotomy (HTO) is one treatment option for young and active patients with unicompartmental osteoarthritis. The success of this procedure substantially depends on the degree of correction of the me...

    Authors: J Lützner, AF Groß, KP Günther and S Kirschner
    Citation: European Journal of Medical Research 2009 14:447
  26. Thoracic outlet syndrome (TOS) is a clinical phenomenon resulting from compression of the neurovascular structures at the superior aperture of the thorax which presents with varying symptoms. Regarding to the ...

    Authors: M Sadeghi-Azandaryani, D Bürklein, A Ozimek, C Geiger, N Mendl, B Steckmeier and J Heyn
    Citation: European Journal of Medical Research 2009 14:443
  27. The diagnostic tools to predict the prognosis in patients suffering from breast cancer (BC) need further improvements. New technological achievements like the gene profiling of circulating tumour cells (CTC) c...

    Authors: E Bölke, K Orth, PA Gerber, G Lammering, R Mota, M Peiper, C Matuschek, W Budach, E Rusnak, S Shaikh, B Dogan, HB Prisack and H Bojar
    Citation: European Journal of Medical Research 2009 14:426
  28. As its central basis for research, the Competence Network for HIV/AIDS (KompNet) established a nationwide cohort study on HIV-positive patients being in medical care in Germany. In this paper, we describe the ...

    Authors: K Jansen, NH Brockmeyer, M Hahn, I Kaul, S Fenske, M Rausch, B Kuhlmann, A Ulmer, E Lauenroth-Mai, T Harrer, M Hower, A Skaletz-Rorowski and C Michalik
    Citation: European Journal of Medical Research 2009 14:415
  29. Breast cancer (BC) represents one of the leading causes of cancer related deaths worldwide. New tools for diagnostic staging and therapeutic monitoring are needed to improve individualized therapies and improv...

    Authors: E Bölke, K Orth, PA Gerber, G Lammering, R Mota, M Peiper, C Matuschek, W Budach, E Rusnak, S Shaikh, B Dogan, HB Prisack and H Bojar
    Citation: European Journal of Medical Research 2009 14:359
  30. The Gasperini syndrome is a very rare brainstem disease characterized by the typical combination of ipsilateral lesions of the cranial nerves V-VII and dissociated contralateral hemihypesthesia, whereas both c...

    Authors: M Krasnianski, T Müller, S Zierz and M Winterholler
    Citation: European Journal of Medical Research 2009 14:413
  31. The aim of the present study was to determine whether regular exercise training (ET) is effective at promoting the mobilization of CPCs and improving their functional activity in patients with recently acquire...

    Authors: M Brehm, F Picard, P Ebner, G Turan, E Bölke, M Köstering, P Schüller, T Fleissner, D Ilousis, K Augusta, M Peiper, Ch Schannwell and BE Strauer
    Citation: European Journal of Medical Research 2009 14:393
  32. In IRCU it is uncertain whether variation of urinary protein, especially non-albumin protein (NAlb-P), is due to the presence of stones or reflects alteration of oxidative metabolism.

    Authors: PO Schwille, A Schmiedl and J Wipplinger
    Citation: European Journal of Medical Research 2009 14:378
  33. Quantitative tests of liver function (QTLF) which are based on the hepatic metabolism or clearance of test substances have been successfully used to predict prognosis of a variety of different liver diseases. ...

    Authors: M Miller, A Kahraman, B Ross, M Beste and G Gerken
    Citation: European Journal of Medical Research 2009 14:369
  34. There is a high comorbidity of schizophrenia and obsessive-compulsory disorder (OCD) associated with more severe symptoms. Standard pharmacotherapy achieve symptom improvement in approximately 60% only.

    Authors: F Hanisch, J Friedemann, J Piro and P Gutmann
    Citation: European Journal of Medical Research 2009 14:367
  35. The preferred immunosuppressive drug for long term treatment of myasthenia gravis (MG) is azathioprine (AZA). Mycophenolate mofetil (MMF) was suggested as an effective and safe second line alternative to AZA.

    Authors: F Hanisch, M Wendt and S Zierz
    Citation: European Journal of Medical Research 2009 14:364
  36. We conducted a single-centre, randomised, double-blinded, placebo-controlled phase II clinical study to test safety and efficacy of a 12-week therapy with low-dose (700 mg/daily) or high-dose (2800 mg/daily) o...

    Authors: N Dauletbaev, P Fischer, B Aulbach, J Gross, W Kusche, U Thyroff-Friesinger, TOF Wagner and J Bargon
    Citation: European Journal of Medical Research 2009 14:352
  37. Only 50% of gallbladder cancers (GBC) are recognized before operation and the remaining tumors are diagnosed during surgery or afterwards by the pathologist. These situations may demand substantial modificatio...

    Authors: F Löhe, G Meimarakis, C Schauer, M Angele, KW Jauch and RJ Schauer
    Citation: European Journal of Medical Research 2009 14:345
  38. In this paper, we describe the main objectives, the study design and the onset of the patient cohort of the German Competence Network for HIV/AIDS (KompNet). Furthermore, we depict sociodemographic and clinica...

    Authors: K Jansen, C Michalik, M Hahn, S Dupke, S Esser, H Jaeger, S Köppe, A Moll, A Plettenberg, RE Schmidt, A Skaletz-Rorowski and NH Brockmeyer
    Citation: European Journal of Medical Research 2009 14:323
  39. Rectal polypectomy causes thinning (or even perforation) of the rectal wall in addition to thermic injury at the polypectomy site.

    Authors: WY Khoder, AJ Becker, B Schlenker, S Tritschler, PJ Bastian and CG Stief
    Citation: European Journal of Medical Research 2009 14:320
  40. Macrolide antibiotics are reported to modulate the production of cytokines in various type of cells. We examined the effect of macrolide antibiotics on inflammatory cytokines (IL-6 and IL-8) and chemical media...

    Authors: A Kamemoto, T Ara, T Hattori, Y Fujinami, Y Imamura and P-L Wang
    Citation: European Journal of Medical Research 2009 14:309
  41. Blood loss during radical prostatectomy has been a long term issue. The aim of this study was to investigate the influence of the training level of the first assistant regarding blood loss in open retropubic r...

    Authors: A Karl, A Buchner, H Beckerv, M Staehler, M Seitz and C Stief
    Citation: European Journal of Medical Research 2009 14:292

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