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  1. Primary osteoporosis is an age-related disease, and the main cause of this disease is the failure of bone homeostasis. Previous studies have shown that primary osteoporosis is associated with gene mutations.

    Authors: Gai-Li Li, Xian-Hua Xu, Bing-Ang Wang, Yi-Min Yao, Yang Qin, Shu-Rong Bai, Jian Rong, Tao Deng and Yong-He Hu
    Citation: European Journal of Medical Research 2014 19:15

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:33

  2. Metaplastic breast carcinoma (MBC) is an uncommon malignancy characterized by the co-existence of two or more cellular types, commonly a mixture of epithelial and mesenchymal components. A case of a female pat...

    Authors: Yu Kang, Shu Kang, Qingchang Li and Xinyu Zheng
    Citation: European Journal of Medical Research 2014 19:14
  3. Airway inflammation, especially neutrophilic airway inflammation, is a cardinal pathophysiologic feature in chronic obstructive pulmonary disease (COPD) patients. The ideal biomarkers characterizing the inflam...

    Authors: Alling Zhu, Dehai Ge, Jingying Zhang, Yue Teng, Cheng Yuan, Mao Huang, Ian M Adcock, Peter J Barnes and Xin Yao
    Citation: European Journal of Medical Research 2014 19:12
  4. Awareness of myocarditis in association with inflammatory bowel diseases is crucial as it bears a rare but serious risk for mortality. This report describes the case of a young Caucasian male, whose heart biop...

    Authors: Varnavas C Varnavas, Nico Reinsch, Mareike Perrey, Felix Nensa, Thomas Schlosser, Hideo A Baba, Guido Gerken, Raimund Erbel, Rolf A Janosi and Antonios Katsounas
    Citation: European Journal of Medical Research 2014 19:11
  5. Osteosarcoma is the most common type of bone cancer and is notorious for its rapid progression. The Notch signaling pathway has recently been shown to be involved in osteosarcoma. As a major sheddase of Notch ...

    Authors: Ren Zhao, Dongjing Ni, Yi Tian, Bing Ni and Aimin Wang
    Citation: European Journal of Medical Research 2014 19:9
  6. Cardiovascular autonomic neuropathy (CAN) is rapidly growing in all populations worldwide. Baroreflex sensitivity (BRS) is easily applied as a diagnostic test to a large number of individuals in the general po...

    Authors: Zi-Hui Tang, Fangfang Zeng, Kuangping Ye, Xiaoling Yu and Linuo Zhou
    Citation: European Journal of Medical Research 2014 19:8
  7. The objective of this study was to evaluate changes in left ventricular ejection fraction (LVEF) and left ventricular remodeling after coronary microembolization (CME) and to investigate the protective effects...

    Authors: Jianying Ma, Juying Qian, Shufu Chang, Zhangwei Chen, Hang Jin, Mengsu Zeng, Yunzeng Zou and Junbo Ge
    Citation: European Journal of Medical Research 2014 19:7
  8. New prognostic markers may be of value in determining survival and informing decisions of adjuvant treatment in the heterogeneous group of soft tissue sarcomas known as malignant fibrous sarcomas (MFS). Increa...

    Authors: Christiane Matuschek, Marcus Lehnhardt, Peter Arne Gerber, Christopher Poremba, Jackson Hamilton, Guido Lammering, Klaus Orth, Wilfried Budach, Hans Bojar, Edwin Bölke and Matthias Peiper
    Citation: European Journal of Medical Research 2014 19:6
  9. The aim of this study was to investigate the relationship between the polymorphisms of the methylenetetrahytrofolate reductase (MTHFR) gene and susceptibility to childhood acute lymphoblastic leukemia (ALL).

    Authors: Xiaolei Li, Qingchuan Liao, Shunguo Zhang and Minling Chen
    Citation: European Journal of Medical Research 2014 19:5
  10. The purpose of this study was to evaluate the efficacy of prenatal ultrasonography and Doppler sonography in detecting isolated ventricular septal defects (VSDs) in a late-second-trimester population.

    Authors: Wei-Hsiu Chiu, Ming-Chon Hsiung, Ran-Chou Chen, Xiao-Min Xiao, Cai-Lin Wu and Tao-Hsin Tung
    Citation: European Journal of Medical Research 2014 19:3
  11. Bosentan is a dual endothelin receptor antagonist initially introduced for the treatment of pulmonary arterial hypertension and recently approved for the treatment of digital ulcers in patients with systemic s...

    Authors: Sonja Hetzer, Bettina Alexandra Buhren, Holger Schrumpf, Edwin Bölke, Stephan Meller, Kai Kammers, Peter Arne Gerber and Bernhard Homey
    Citation: European Journal of Medical Research 2014 19:2
  12. High-intensity focused ultrasound is a valuable tool for minimally invasive tumour ablation. However, due to the air content in ventilated lungs, lung tumours have never been treated with high-intensity focuse...

    Authors: Frank Wolfram, Carsten Boltze, Harald Schubert, Sabine Bischoff and Thomas Günther Lesser
    Citation: European Journal of Medical Research 2014 19:1
  13. Intervertebral disc (IVD) cells experience a broad range of physicochemical stimuli under physiologic conditions, including alterations in their osmotic environment. At present, the molecular mechanisms underl...

    Authors: Wenzhi Zhang, Xu Li, Xifu Shang, Qichun Zhao, Yefeng Hu, Xiang Xu, Rui He, Liqun Duan and Feng Zhang
    Citation: European Journal of Medical Research 2013 18:62

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:32

  14. Tumor-derived exosomes have been viewed as a source of tumor antigens that can be used to induce anti-tumor immune responses. In the current study, we aim to investigate the regulatory effect of the epigenetic...

    Authors: Wenhua Xiao, Weiwei Dong, Caihong Zhang, Gaowa Saren, Paili Geng, Huixia Zhao, Quiwen Li, Jianhua Zhu, Guanghui Li, Shufang Zhang and Ming Ye
    Citation: European Journal of Medical Research 2013 18:61
  15. Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson’s disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, in...

    Authors: Clelia Pellicano, Dario Benincasa, Alessandra Fanciulli, Pamela Latino, Morena Giovannelli and Francesco E Pontieri
    Citation: European Journal of Medical Research 2013 18:60
  16. Hepatocellular carcinoma (HCC) is the fifth most common malignant tumor in men and the seventh in women and understanding the molecular mechanisms of HCC and establishing more effective therapies are critical ...

    Authors: Qin Wang, Jun Zhou, Dewu Zhong, Qunwei Wang and Jiangsheng Huang
    Citation: European Journal of Medical Research 2013 18:59

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:38

  17. Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. In this study, the effects of triptolide on lipopolysaccharide (LPS)-induced ALI in rats were investigated.

    Authors: Jianling Gao, Ying Zhan, Jun Chen, Lina Wang and Jianping Yang
    Citation: European Journal of Medical Research 2013 18:58

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:35

  18. The aim of this study was to establish an osteosarcoma (OS) associated protein-protein interaction network and explore the pathogenesis of osteosarcoma.

    Authors: Bi-Yong Deng, Ying-Qi Hua and Zheng-Dong Cai
    Citation: European Journal of Medical Research 2013 18:57

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:40

  19. Prostate stem cell antigen (PSCA) is upregulated in prostate cancer tissues. Here we aimed to study the therapeutic efficacy of a monoclonal antibody of PSCA-labeled I131 (I131-PSCA-mAb) in orthotopic mouse model...

    Authors: Shengqiang Yu, Fan Feng, Ke Wang, Changping Men, Chunhua Lin, Qingzuo Liu, Diandong Yang and Zhenli Gao
    Citation: European Journal of Medical Research 2013 18:56
  20. In our study, we used meta-analysis to study the efficacy of the tourniquet on ankle trauma surgery. Postoperative infection rate, deep venous thrombosis incidence, hospital stay, and joint range of motion wer...

    Authors: Xinhua Jiang, Baoqing Yu, Wei Qu and Jiawen He
    Citation: European Journal of Medical Research 2013 18:55

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:34

  21. Nonalcoholic fatty liver disease (NAFLD) is a risk for hepatocellular carcinoma (HCC), but the association between a high-fructose diet and HCC is not fully understood. In this study, we investigated whether a...

    Authors: Ryo Kumamoto, Hirofumi Uto, Kohei Oda, Rie Ibusuki, Shirou Tanoue, Shiho Arima, Seiichi Mawatari, Kotaro Kumagai, Masatsugu Numata, Tsutomu Tamai, Akihiro Moriuchi, Hiroshi Fujita, Makoto Oketani, Akio Ido and Hirohito Tsubouchi
    Citation: European Journal of Medical Research 2013 18:54
  22. To study the efficacy and safety of cilostazol on ischemic stroke prevention and treatment, systematic reviews of related clinical randomized controlled trials were analyzed.

    Authors: Yining Qian and Qi Bi
    Citation: European Journal of Medical Research 2013 18:53

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:39

  23. Increased metastasis has been proved to be associated with a poor prognosis for hepatocellular carcinoma (HCC). There are higher-level expressions of integrin α6 in the tissues of HCC patients with a higher fa...

    Authors: Guannan Lv, Tianjing Lv, Shifeng Qiao, Wei Li, Weiran Gao, Xiaohui Zhao and Jikun Wang
    Citation: European Journal of Medical Research 2013 18:52
  24. The main purpose of this study was to assess the feasibility and relevant applying techniques of total thyroidectomy for thyroid carcinoma with a modified Miccoli’s approach.

    Authors: Xiang Shen, Zhi-ming Miao, Wei Lu, Da-li Gu, Dan Yang, Hao Shen and Feng Geng
    Citation: European Journal of Medical Research 2013 18:51
  25. Several studies demonstrated acute inflammatory response following traumatic injury. Inflammatory response during surgical interventions was verified by a significant increase of endotoxin plasma levels and a ...

    Authors: Klaus Orth, Wolfram Trudo Knoefel, Martijn van Griensven, Christiane Matuschek, Matthias Peiper, Holger Schrumpf, Peter Arne Gerber, Wilfried Budach, Edwin Bölke, Bettina Alexandra Buhren and Matthias Schauer
    Citation: European Journal of Medical Research 2013 18:50
  26. The efficacy of highly active antiretroviral therapy (HAART) in the treatment of HIV infection is influenced by factors such as potency of applied drugs, adherence of the patient, and resistance-associated mut...

    Authors: Mark Oette, Stefan Reuter, Rolf Kaiser, Björn Jensen, Thomas Lengauer, Gerd Fätkenheuer, Heribert Knechten, Martin Hower, Abdurrahman Sagir, Herbert Pfister and Dieter Häussinger
    Citation: European Journal of Medical Research 2013 18:48
  27. The aim of this study is to investigate the effects of polyphenol extract from Phyllanthus emblica (PEEP) on cervical cancer cells and to explore the underlying mechanism.

    Authors: Xinxian Zhu, Jianjun Wang, Yang Ou, Weiwei Han and Huaifang Li
    Citation: European Journal of Medical Research 2013 18:46
  28. Post-transplant anemia (PTA) has long been a less-recognized complication in kidney transplant recipients, and its prevalence also tends to be underestimated. This study sought to evaluate the prevalence, mana...

    Authors: Zhixian Wu, Junqi Guo, Lianming Liao, Weizhen Wu, Shunliang Yang and Jianming Tan
    Citation: European Journal of Medical Research 2013 18:45
  29. Primary hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. However, the molecular pathogenesis of HCC is not well-understood, and the prognosis for patients with HCC remains ve...

    Authors: Deyong Kong, Heming Chen, Weiqun Chen, Shuiyi Liu, Hui Wang, Tangwei Wu, Hongda Lu, Qingzhi Kong, Xiaodong Huang and Zhongxin Lu
    Citation: European Journal of Medical Research 2013 18:44

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:31

  30. Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is associated with frequent adverse effects, such as hyper-...

    Authors: Said Hilton, Heike Heise, Bettina Alexandra Buhren, Holger Schrumpf, Edwin Bölke and Peter Arne Gerber
    Citation: European Journal of Medical Research 2013 18:43
  31. Our purpose was to investigate the clinical efficacy of arthroscope-assisted acromioclavicular ligament reconstruction in combination with double endobutton coracoclavicular ligament reconstruction for the tre...

    Authors: Haoqing Li, Chuanshun Wang, Jiandong Wang, Kai Wu and Donghua Hang
    Citation: European Journal of Medical Research 2013 18:42
  32. miRNAs are a class of small non-coding RNA molecules that play an important role in the pathogenesis of human diseases through negative regulation of gene expression. Although miRNA-10b (miR-10b) has been impl...

    Authors: Yi Liu, Minghui Li, Guoqing Zhang and Zuoliang Pang
    Citation: European Journal of Medical Research 2013 18:41
  33. With an aging society and raised expectations, joint replacement surgery is likely to increase significantly in the future. The development of postoperative complications following joint replacement surgery (f...

    Authors: Stephen F Hughes, Beverly D Hendricks, David R Edwards, Salah S Bastawrous and Jim F Middleton
    Citation: European Journal of Medical Research 2013 18:40
  34. A 62 year-old patient with therapy-refractory pouchitis after proctocolectomy for ulcerative colitis was admitted with hematochezia and abdominal discomfort. A malignant melanoma (MM) was found after repeated ...

    Authors: Philipp Lingohr, Thomas Galetin, Hanno Matthaei, Eberhard Straub, Azin Jafari, Edwin Bölke, Jörg C Kalff and Karl-Heinz Vestweber
    Citation: European Journal of Medical Research 2013 18:39
  35. The aim of this study was to identify key genes and novel potential therapeutic targets related to gastric cancer (GC) by comparing cancer tissue samples and healthy control samples using DNA microarray analysis.

    Authors: Yong Jin and Wei Da
    Citation: European Journal of Medical Research 2013 18:37

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:30

  36. Prostate cancer (PCa) originating from the prostate base may intrude into the urinary bladder and may be misdiagnosed as bladder cancer. In this retrospective study, we reviewed the clinic data on PCa cases wh...

    Authors: Ranlu Liu, Xiaoqiang Xie, Zhihong Zhang and Yong Xu
    Citation: European Journal of Medical Research 2013 18:36
  37. Hepatocellular carcinoma (HCC) is one of the most common types of cancer worldwide. Despite several efforts to elucidate molecular mechanisms involved in this cancer, they are still not fully understood.

    Authors: Lingyan Zhang, Ying Guo, Bibo Li, Juan Qu, Chunbao Zang, Fang Li, Ying Wang, Hua Pang, Shaolin Li and Qingjun Liu
    Citation: European Journal of Medical Research 2013 18:35
  38. There are two completely contradictory views regarding the impact of human bone-marrow-derived mesenchymal stem cells (hMSCs) on hepatocellular carcinomas (HCCs). The aim of this study was to investigate the e...

    Authors: Tianran Li, Bin Song, Xiangke Du, Zhengmao Wei and Tianlong Huo
    Citation: European Journal of Medical Research 2013 18:34
  39. In recent years, many advances in pancreatic surgery have been achieved. Nevertheless, the rate of pancreatic fistula following pancreatic tail resection does not differ between various techniques, still reach...

    Authors: Aycan Akca, Peter E Goretzki, Denis Wirowski, Marc A Renter, Edwin Bölke, Christiane Matuschek, Peter Arne Gerber and Bernhard J Lammers
    Citation: European Journal of Medical Research 2013 18:33
  40. Thiamine deficiency has suggested to be linked to several insulin-resistance complications. In this study, we aim to associate circulating thiamine levels among cardiometabolic parameters in an Arab cohort usi...

    Authors: Nasser M Al-Daghri, Omar S Al-Attas, Khalid M Alkharfy, Majed S Alokail, Sherif H Abd-Alrahman and Shaun Sabico
    Citation: European Journal of Medical Research 2013 18:32
  41. With the Bonebridge, a new bone-anchored hearing aid has been available since March 2012. The objective of the study was to analyse the visualisation of the implant itself as well as its impact on the represen...

    Authors: Christian Güldner, Julia Heinrichs, Rainer Weiß, Annette Paula Zimmermann, Benjamin Dassinger, Siegfried Bien, Jochen Alfred Werner and Isabell Diogo
    Citation: European Journal of Medical Research 2013 18:30
  42. Cancer is the result of a complex multistep process that involves the accumulation of sequential alterations of several genes, including those encoding microRNAs (miRNAs) that have critical roles in the regula...

    Authors: Yahong Xu, Shunwen Luo, Yang Liu, Jian Li, Yi Lu, Zhigang Jia, Qihua Zhao, Xiaoping Ma, Minghui Yang, Yue Zhao, Ping Chen and Yu Guo
    Citation: European Journal of Medical Research 2013 18:29

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:43

  43. It has been demonstrated that urokinase-type plasminogen activator (uPA) is involved in tumor cell metastasis by degrading the extracellular matrix. However, there is little direct evidence of clinical uPA sys...

    Authors: Youcheng Ding, Hui Zhang, Mingan Zhong, Zhuqing Zhou, Zhixiang Zhuang, Hua Yin, Xujing Wang and Zhenggang Zhu
    Citation: European Journal of Medical Research 2013 18:28

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