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  1. To evaluate the prognostic value of skeletal muscle index (SMI) and its change in patients with hepatocellular carcinoma (HCC) experiencing curative hepatectomy plus adjuvant transarterial chemoembolization (T...

    Authors: Siwei Yang, Zhiyuan Zhang, Tianhao Su, Jianan Yu, Shasha Cao, Haochen Wang and Long Jin
    Citation: European Journal of Medical Research 2022 27:131
  2. In recent years, with the increasing incidence of colorectal cancer (CRC) and its high fatality rate, CRC has seized the attention of the world. And liver metastasis, as the main cause of death of CRC, has bec...

    Authors: Mengdi Hao, Kun Wang, Yuhan Ding, Huimin Li, Yin Liu and Lei Ding
    Citation: European Journal of Medical Research 2022 27:130
  3. Patients who exceed their expected length of stay in the hospital come at a cost to stakeholders in the healthcare sector as bed spaces are limited for new patients, nosocomial infections increase and the outc...

    Authors: Chinedu I. Ossai, David Rankin and Nilmini Wickramasinghe
    Citation: European Journal of Medical Research 2022 27:128
  4. The human JC polyomavirus (JCPyV) has been detected in colorectal cancer (CRC) tissues and is suggested to contribute to CRC tumorigenesis. The rearrangement of the JCPyV regulatory region is supposedly associ...

    Authors: Chuan-Yin Fang, San-Yuan Chen, Bo-Xiu Hsiao, Hsin-Yi Huang, Yi-Ju Chen, Chun-Liang Tung and Chiung-Yao Fang
    Citation: European Journal of Medical Research 2022 27:127
  5. Cleft lip repair surgery always results in visible scarring. It has been proved that scar formation can be reduced by inhibiting the p38 mitogen-activated protein kinases (p38MAPKs) signaling pathway. However,...

    Authors: Qian Ding, Jin Yue, Ling-fa Xue, Yao-xiang Xu and Wen-lin Xiao
    Citation: European Journal of Medical Research 2022 27:126
  6. Hypospadias is one of the most common congenital diseases of the genitourinary system in children. The European Association of Urology (EAU) Guidelines recommend that children undergoing hypospadias surgery sh...

    Authors: Gaochen Bai, Feng Liang, Tianxin Zhao, Fuming Deng, Kai Fu, Xiong Chen, Zhongmin Li, Liyu Zhang, Wei Jia, Wen Fu and Guochang Liu
    Citation: European Journal of Medical Research 2022 27:125
  7. The effectiveness of laparoscopic total gastrectomy with D2 lymphadenectomy (LTGD2) remains controversial. This meta-analysis compares surgical and survival outcomes of LTGD2 and open total gastrectomy with D2...

    Authors: Yongpu Yang, Yuyan Chen, Yilin Hu, Ying Feng, Qinsheng Mao and Wanjiang Xue
    Citation: European Journal of Medical Research 2022 27:124
  8. Desmoids are rare fibroblastic tumours whose treatment in any individual case presents a persistent challenge. We endeavoured to evaluate various clinicopathological factors contributing to tumour behaviour.

    Authors: Misbah Khan, Max Almond, Samuel Ford and Anant Desai
    Citation: European Journal of Medical Research 2022 27:123
  9. As precision medicine gradually played an inaccessible role in cancer treatment, there was an urgent need to explore biomarkers or signatures for predicting cancer prognosis. Currently, little was known about ...

    Authors: Shiwei Liu, Yang Yu, Yi Wang, Bingye Zhu and Bangmin Han
    Citation: European Journal of Medical Research 2022 27:122
  10. Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide. P21 activated kinase 4 (PAK4) and Breast cancer anti-estrogen resistance 3 (BCAR3) have been reported to be involved in nume...

    Authors: Junjie Hou, Xuguang Mi, Ning Liu, Xiaonan Li, Xiao-nan Li, Ying Yang, Xiaodan Lu, Yanqiu Fang and Ning-Yi Jin
    Citation: European Journal of Medical Research 2022 27:121
  11. Pseudomonas aeruginosa is an adaptable bacterial pathogen that infects a variety of organs, including the respiratory tract, vascular system, urinary tract, and central nervous system, causing significant morbidi...

    Authors: Ashish Kothari, Shyam Kishor Kumar, Vanya Singh, Prashant Kumar, Karanvir Kaushal, Atul Pandey, Neeraj Jain and Balram Ji Omar
    Citation: European Journal of Medical Research 2022 27:120
  12. Plastic and reconstructive surgery (PRS) remains highly relevant to the unmet need for surgery in Malawi. Better understanding the current PRS landscape and its barriers may help address some of these challeng...

    Authors: Chifundo Msokera, Meredith Xepoleas, Zachary J. Collier, Priyanka Naidu and William Magee III
    Citation: European Journal of Medical Research 2022 27:119
  13. The aim of this study was to investigate the renoprotective effects of exosomes derived from rat bone marrow mesenchymal stem cells (rBMSCs) in a rat model of 5/6 nephrectomy (Nx)-induced chronic kidney diseas...

    Authors: Feng Wan, Ru-chun Yang, Yue-wen Tang, Xuan-li Tang, Tian Ye, Jie Zheng, Hua-qin Zhang and Yi Lin
    Citation: European Journal of Medical Research 2022 27:118
  14. Chronic renal failure (CRF) is a progressive loss of renal function that lead to reduced sodium filtration and inappropriate suppression of tubular reabsorption that ultimately leads to volume expansion. The a...

    Authors: Moustafa Mahmoud Hamdy, Mahran S. Abdel-Rahman, Dalia M. Badary and Mahmoud S. Sabra
    Citation: European Journal of Medical Research 2022 27:117
  15. Intrahepatic cholangiocarcinoma (ICC), highly invasive and highly heterogeneous, has a poor prognosis. It has been confirmed that many risk factors are associated with ICC including intrahepatic lithiasis, pri...

    Authors: Yinghui Song, Mengting Cai, Yuhang Li and Sulai Liu
    Citation: European Journal of Medical Research 2022 27:116

    The Correction to this article has been published in European Journal of Medical Research 2022 27:166

  16. Exostosin like glycosyltransferase 3 (EXTL3) had been reported to be associated with immune deficiency and play prognostic roles in various cancers. However, little is known about the associations between EXTL...

    Authors: Pingan Chang, Shenglan Chen, Xiumei Chang, Jiaxi Zhu, Qingsheng Tang and Limin Ma
    Citation: European Journal of Medical Research 2022 27:115
  17. Thyroid hormones play an instrumental role in chondrogenic differentiation and matrix maturation. However, studies investigating the relationship between thyroid function and the risk of osteoarthritis (OA) re...

    Authors: Shuai Chen, Xiaohe Sun, Guowei Zhou, Jie Jin and Zhiwei Li
    Citation: European Journal of Medical Research 2022 27:114
  18. The placental examination provides important information about the effect of maternal abnormalities on the placenta or the cause of preterm delivery, fetal growth restriction, or fetal neurodevelopmental damag...

    Authors: Setareh Akhavan, Sedigheh Borna, Alireza Abdollahi, Mamak Shariat and Narges Zamani
    Citation: European Journal of Medical Research 2022 27:113
  19. Metabolic-associated fatty liver disease (MAFLD), formerly known as non-alcoholic fatty liver disease, is the leading cause of liver disease that can ultimately lead to cirrhosis. Identifying a screening marke...

    Authors: Sahar Samimi, Sahar Rajabzadeh, Soghra Rabizadeh, Manouchehr Nakhjavani, Pooria Nakhaei, Foroogh Alborzi Avanaki and Alireza Esteghamati
    Citation: European Journal of Medical Research 2022 27:112
  20. Abnormal vitamin D is prevalent in critical care settings, but its association with prognosis remains unclear. The study aimed to investigate the prevalence and predictors of abnormal blood 25-hydroxyvitamin D...

    Authors: Juntao Xie, Qingui Chen and Dejian He
    Citation: European Journal of Medical Research 2022 27:111
  21. This study aimed to investigate the effect of conventional drugs combined with acupuncture therapy on the conversion of sinus rhythm in patients with atrial fibrillation.

    Authors: Yibing Li, Jinming Song, Bangqi Wu, Xuhui Wang, Lin Han and Zhenzhen Han
    Citation: European Journal of Medical Research 2022 27:110
  22. Based on the social-ecological model, this study aimed to comprehensively explore factors affecting the risk of ischemic cerebrovascular disease (ICVD) in postmenopausal women to provide theoretical bases for ...

    Authors: Chun-Jun Yang, Dong-Mei Wang, Tong Wang and Ying Song
    Citation: European Journal of Medical Research 2022 27:109
  23. Bacteria associated with dental caries have a high ability to produce organic acids from dietary carbohydrates during growth and metabolism under acidic conditions. In contrast, many symbiotic bacteria produce...

    Authors: Samaneh Vaziriamjad, Mobina Solgi, Farideh Kamarehei, Fatemeh Nouri and Mohammad Taheri
    Citation: European Journal of Medical Research 2022 27:108
  24. Glutamate signaling activates MAPK and PI3K/AKT pathways in tumor cells. Treatment with riluzole, a glutamate release inhibitor, has been previously shown to be safe in melanoma patients and produced biologic ...

    Authors: Ann W. Silk, Biren Saraiya, Roman Groisberg, Nancy Chan, Kristen Spencer, Eugenia Girda, Weichung Shih, Marisa Palmeri, Tracie Saunders, Robert M. Berman, Vlad Coric, Suzie Chen, Andrew Zloza, Joshua Vieth, Janice M. Mehnert and Jyoti Malhotra
    Citation: European Journal of Medical Research 2022 27:107
  25. Chronic inflammatory disorders in atrial fibrillation (AF) contribute to the onset of ischemic stroke. Systemic immune inflammation index (SIII) and system inflammation response index (SIRI) are the two novel ...

    Authors: Kai-bin Lin, Feng-hua Fan, Ming-qi Cai, Yin Yu, Chuan-liang Fu, Lu-yue Ding, Yu-dong Sun, Jia-wen Sun, Yong-wang Shi, Zhi-feng Dong, Min-Jie Yuan, Shuai Li, Yan-peng Wang, Kan-kai Chen, Ji-ni Zhu, Xin-wei Guo…
    Citation: European Journal of Medical Research 2022 27:106
  26. Androgen deprivation therapy (ADT) is still the first-line treatment of prostate cancer (PCa). However, after a certain period of therapy, primary PCa inevitably progresses into castration-resistant PCa (CRPC)...

    Authors: Xi Chen, Yechen Wu, Xinan Wang, Chengdang Xu, Licheng Wang, Jingang Jian, Denglong Wu and Gang Wu
    Citation: European Journal of Medical Research 2022 27:105
  27. Bone biopsies are often necessary to make a diagnosis in the case of irregular bone structures of the jaw. A 3D-printed surgical guide may be a helpful tool for enhancing the accuracy of the biopsy and for ens...

    Authors: Lukas Postl, Thomas Mücke, Stefan Hunger, Sabina Noreen Wuersching, Svenia Holberg, Oliver Bissinger, Rainer Burgkart, Michael Malek and Stefan Krennmair
    Citation: European Journal of Medical Research 2022 27:104
  28. The objective of the study was to demonstrate the cortical thickness character in the humeral surgical neck region using 3D cortical bone mapping technique and try to illustrate its morphological changes with ...

    Authors: Jialiang Guo, Yali Zhou, Meishuang Shang, Wei Chen, Zhiyong Hou, Yingze Zhang and Weichong Dong
    Citation: European Journal of Medical Research 2022 27:102
  29. The connection between initial viral cycle threshold (Ct) values of the SARS-CoV-2 with symptoms and hospital course is not clearly studied.

    Authors: Salma AlBahrani, Mohammed Alghamdi, Nawaf Zakary, Arulanantham Zechariah Jebakumar, Samirah Jamaan AlZahrani, Mohamed Hany ElGezery, Khaled Omar Abdallah and Jaffar A. Al-Tawfiq
    Citation: European Journal of Medical Research 2022 27:101
  30. Leiomyosarcoma originating from the renal vein (RVLMS) is extremely rare. RVLMS lacks specific clinical manifestations and specific imaging features. This article discusses the epidemiological characteristics ...

    Authors: Qais Baheen, Hai Bi, Kai Wang, Min Lu, Hongxian Zhang and Lulin Ma
    Citation: European Journal of Medical Research 2022 27:100
  31. Pancreatic calcifications (PC) are considered specific for chronic pancreatitis (CP), but PC may also be present in non-CP diseases. The aims are to understand the pattern of calcifications in different diseas...

    Authors: Wei Wang, Li Chai, Naiyi Zhu, Qingrou Wang, Yiran Zhou and Weimin Chai
    Citation: European Journal of Medical Research 2022 27:99
  32. Antibiotic resistance is a major global public health problem. The primary cause of antibiotic resistance is inappropriate antibiotic use. In this study, we aimed to verify whether the monthly evaluation of an...

    Authors: Qiong Yang, Fangfang Yuan, Li Li, Jianfeng Jin and Junhong He
    Citation: European Journal of Medical Research 2022 27:98
  33. The influence of immunosuppressive therapy on immunogenicity after COVID-19 vaccination remains unclear. This study surveys patients who receive immunosuppressive therapy about whether or not they paused their...

    Authors: Dominik Schröder, Stephanie Heinemann, Gloria Heesen, Frank Klawonn, Marie Mikuteit, Jacqueline Niewolik, Sandra Steffens, Georg Behrens, Alexandra Jablonka and Frank Müller
    Citation: European Journal of Medical Research 2022 27:97
  34. Neuromyelitis optica spectrum disorders (NMOSDs) are blindness-causing neuritis; their pathogenesis is still not fully elucidated. Although it has been determined that Bruton tyrosine kinase (BTK) and NF-κB ar...

    Authors: Huimin Qiao, Zhuofeng Mao, Wei Wang, Xin Chen, Suhuan Wang, Haolong Fan, Tianyi Zhao, Huiqing Hou and Mei Dong
    Citation: European Journal of Medical Research 2022 27:96
  35. Clinical research publications have become the dominant source and basis of clinical evidence-based decision-making. Exploring the type and quantity of clinical research publications in the PubMed database is ...

    Authors: Xiyi Zhao, Hao Jiang, Jianyun Yin, Hongchao Liu, Ruifang Zhu, Shencong Mei and Chang-tai Zhu
    Citation: European Journal of Medical Research 2022 27:95
  36. To describe, through a literature review, the results and benefits of oral and topical probiotics for adult patients with atopic dermatitis.

    Authors: Camila Stofella Sodré, Mayra Stambovsky Vieira, Juliany Lima Estefan, Cristiane Moraes, Fernanda Sampaio Cavalcante, Kátia Regina Netto dos Santos and Dennis de Carvalho Ferreira
    Citation: European Journal of Medical Research 2022 27:94
  37. Alzheimer’s disease (AD) as a neurodegenerative disease occupies 3/5–4/5 cases among patients with dementia, yet its pathogenetic mechanism remains unclear. Geraniol, on the other hand, is a well-known extract...

    Authors: Ying Liu, Shujing Zhou, Xufeng Huang and Hafiz Muzzammel Rehman
    Citation: European Journal of Medical Research 2022 27:93
  38. Endocrine orbitopathy is typically treated by resecting orbital walls. This procedure reduces intraorbital pressure by releasing intraorbital tissue, effectively alleviating the symptoms. However, selection of...

    Authors: Matthias Krause, Michael-Tobias Neuhaus, Ina Sterker, Alexander K. Bartella, Annika Schönfeld, Bernd Lethaus, Rüdiger Zimmerer and Evgeny Gladilin
    Citation: European Journal of Medical Research 2022 27:92
  39. Obesity is very common in patients with schizophrenia. We aimed to evaluate the influencing factors of obesity in community patients with deficit schizophrenia, to provide implication for schizophrenia managem...

    Authors: Na Yong, Jiyang Pan, Xuehua Li, Ling Yu and Xin Hou
    Citation: European Journal of Medical Research 2022 27:90
  40. Malignancy-related hypercalcemia is a leading cause of hypercalcemia among hospitalized patients that carries poor prognosis. Parathyroid carcinoma is a rare form of primary hyperparathyroidism that may be ass...

    Authors: Marc Scheen, Grzegorz Nowak, Bienvenido Sanchez and Daniel Teta
    Citation: European Journal of Medical Research 2022 27:89
  41. Currently, there are relatively few studies on the effects of changes in oestrogen and androgen levels on prostatic microvessel density (MVD). This article aimed to study the changes in prostatic MVD in Spragu...

    Authors: Bo Wang, Di Pan, Yong Ban, Zhaolin Sun, Ye Tian and Guangheng Luo
    Citation: European Journal of Medical Research 2022 27:87
  42. To locate an anastomosable constant perforator of the radial artery on the proximal forearm using ultrasonography and describe the application of a free radial artery flap based on a single proximal perforator...

    Authors: Guangzhi Wu, Zhan Zhang, Fan Zhang, Yiqun Zhang, Qianqian Wang and Wei Yu
    Citation: European Journal of Medical Research 2022 27:85
  43. During the last 2 years, in the Kurdistan Region, Northern Iraq, there were thousands of COVID-19 cases that have not been reported officially, but diagnosed and confirmed by private laboratories and private h...

    Authors: Hemn Muhammed Mustafa, Darya Saeed Abdulateef and Heshu Sulaiman Rahman
    Citation: European Journal of Medical Research 2022 27:84
  44. C-reactive protein (CRP) is an important biomarker of inflammation and plays a pivotal role in predicting the clinical prognosis of cardiovascular and cerebrovascular diseases. However, the mechanism of inflam...

    Authors: Tan Li, Qiannan Yu, Yiqing Wang, Xiuying Cai, Yan Kong, Hongru Zhao, Shanshan Diao, Yiren Qin and Qi Fang
    Citation: European Journal of Medical Research 2022 27:83
  45. Vaccination against SARS-CoV-2 has been the main tool to contain the pandemic. The rush development of the 3 vaccines and their expedited approval have led to inoculation of millions of patients around the wor...

    Authors: Noemi F. Freise, Milena Kivel, Olaf Grebe, Christian Meyer, Bahram Wafaisade, Matthias Peiper, Tobias Zeus, Jan Schmidt, Judith Neuwahl, Danny Jazmati, Tom Luedde, Edwin Bölke, Torsten Feldt, Björn Erik Ole Jensen, Johannes Bode, Verena Keitel…
    Citation: European Journal of Medical Research 2022 27:80

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