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  1. Survivors of critical illness are frequently left with a long-lasting disability. We hypothesised that patients who developed delirium during ICU stay, compared with patients who did not, would have worse heal...

    Authors: Beatriz Lobo-Valbuena, Rosario Molina, Raúl Castañeda-Vozmediano, Leire Lopez de la Oliva Calvo, Ana Abella, María-Mercedes Garcia-Arias, Irene Salinas Gabiña and Federico Gordo
    Citation: European Journal of Medical Research 2023 28:560
  2. Little is known about the performance of severity indices for indicating intensive care and predicting mortality in the Intensive Care Unit (ICU) of trauma patients. This study aimed to compare the performance...

    Authors: Tatiane Gonçalves Gomes de Novais do Rio, Lilia de Souza Nogueira, Fernanda Rodrigues Lima, Carolina Cassiano and Diogo de Freitas Valeiro Garcia
    Citation: European Journal of Medical Research 2023 28:559
  3. Understanding the mechanisms and identifying effective treatments for the COVID-19 outbreak are imperative. Therefore, this study aimed to assess the antioxidant status and oxidative stress parameters as poten...

    Authors: Alireza Bastin, Fatemeh Abbasi, Narges Roustaei, Jahangir Abdesheikhi, Hossein Karami, Mohammad Gholamnezhad, Mahdieh Eftekhari and Amirhossein Doustimotlagh
    Citation: European Journal of Medical Research 2023 28:558
  4. Liver stiffness (LS) is regarded as an indicator of the stages of liver fibrosis and liver cirrhosis. Numerous studies have investigated the relationship between body mass index (BMI) and LS; however, the conc...

    Authors: Yuwei Liu, Sheng Yuan, Jing Zuo, Sha Liu, Xiaoyan Tang, Xia Li, Dongai Yao and Yalei Jin
    Citation: European Journal of Medical Research 2023 28:557
  5. SARS-CoV-2 infections caused mild-to-moderate illness. However, a sizable portion of infected people experience a rapid progression of hyper-inflammatory and hypoxic respiratory illness that necessitates an ef...

    Authors: Mukta Verma, Neha Rawat, Ritu Rani, Manju Singh, Aditi Choudhary, Sarfaraz Abbasi, Manish Kumar, Sachin Kumar, Ankur Tanwar, Bishnu Raman Misir, Sangeeta Khanna, Anurag Agrawal, Mohammed Faruq, Shalini Rai, Richa Tripathi, Anil Kumar…
    Citation: European Journal of Medical Research 2023 28:556
  6. Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease in China. Our study aimed to evaluate the screening value of the fatty liver index (FLI), hepatic steatosis...

    Authors: Yanbo Guo, Yunhua Hu, Jing Yang, Rulin Ma, Xianghui Zhang, Heng Guo, Xinping Wang, Yu Li, Xinyu Peng, Shijie Zhang, Jia He and Shuxia Guo
    Citation: European Journal of Medical Research 2023 28:555
  7. The main problem of positron emission tomography/computed tomography (PET/CT) for lymph node (LN) staging is the high false positive rate (FPR). Thus, we aimed to explore a clinico-biological-radiomics (CBR) m...

    Authors: Caiyue Ren, Fuquan Zhang, Jiangang Zhang, Shaoli Song, Yun Sun and Jingyi Cheng
    Citation: European Journal of Medical Research 2023 28:554
  8. There is no report about the direct relationship between m6A modification and androgen receptor (AR)-related genes in prostate cancer (PC). We aimed to study the mechanisms of m6A methylation in regulating the...

    Authors: Qihong Nie, Xiaoyuan Wu, Yongming Huang, Tao Guo, Jin Kuang and Chuance Du
    Citation: European Journal of Medical Research 2023 28:552
  9. Thromboangiitis obliterans (TAO) is one of the most common types of peripheral arterial disease (PAD). This study aimed to explore the characteristics of the top 100 most cited articles in the TAO.

    Authors: Zhenxing Liu, Weiwei Ning, Jinlong Liang, Tao Zhang, Qingxu Yang, Jie Zhang and Ming Xie
    Citation: European Journal of Medical Research 2023 28:551
  10. Disease-related stress can trigger the occurrence of herpes zoster (HZ). Fatty liver disease (FLD) can have adverse effects on the human body and may induce stress in affected individuals. In this study, we in...

    Authors: Cheng-Wei Yu, Chia-Hung Chen, Yung-Chi Cheng, Wen-Che Hsieh, Tzu-Ju Hsu, Fuu-Jen Tsai and Chao-Yu Hsu
    Citation: European Journal of Medical Research 2023 28:550
  11. A scientific and comprehensive analysis of the current status and trends in the field of cancer-associated fibroblast (CAF) research is worth investigating. This study aims to investigate and visualize the dev...

    Authors: Dun Yuan, Bo-Wen Zheng, Bo-Yv Zheng, Hua-Qing Niu, Ming-Xiang Zou, Song-Lin Liu and Fu-Sheng Liu
    Citation: European Journal of Medical Research 2023 28:549
  12. Head and neck squamous cell carcinoma (HNSCC) is an extremely heterogeneous and metastatic disease. Anoikis, which is a specific type of programmed apoptosis, is involved in tumor metastasis, tissue homeostasi...

    Authors: Hongxia Deng, Zhengyu Wei, Juan Du, Zhisen Shen and Chongchang Zhou
    Citation: European Journal of Medical Research 2023 28:548
  13. Triptonodiol is a very promising antitumor drug candidate extracted from the Chinese herbal remedy Tripterygium wilfordii Hook. F., and related studies are underway.

    Authors: Feng Jin, Xiaochen Ni, Shilong Yu, Xiaomin Jiang, Jun Zhou, Defang Mao, Yanqing Liu and Feng Wu
    Citation: European Journal of Medical Research 2023 28:547
  14. Tumor size plays an important role in the staging and treatment of thyroid carcinoma. A tumor with a maximum diameter of 1 cm or less is referred to as microcarcinoma. It is unclear if the clinicopathological ...

    Authors: Xin Wu, Binglu Li and Chaoji Zheng
    Citation: European Journal of Medical Research 2023 28:546
  15. umor cells, immune cells and stromal cells jointly modify tumor development and progression. We aim to explore the potential effects of tumor purity on the immune microenvironment, genetic landscape and progno...

    Authors: Qiang Su, Yongbei Zhu, Bingxi He, Bin Dai, Wei Mu and Jie Tian
    Citation: European Journal of Medical Research 2023 28:545
  16. Alzheimer’s disease (AD) is a worldwide public health problem and is difficult to cure. Drugs aimed at slowing the progression of the disease have been developed, with the Food and Drug Administration (FDA) gr...

    Authors: Wenxue Wu, Yi Ji, Zilan Wang, Xiaoxiao Wu, Jiaxuan Li, Feng Gu, Zhouqing Chen and Zhong Wang
    Citation: European Journal of Medical Research 2023 28:544
  17. Gastroparesis has a substantial impact on the quality of life but has limited treatment options, which makes it a public health concern. No bibliometric studies on gastroparesis have been published thus far. T...

    Authors: Meng Li, Ning Gao, Shaoli Wang, Yufeng Guo and Zhen Liu
    Citation: European Journal of Medical Research 2023 28:543
  18. There have been massive studies to develop an effective vaccine against SARS-CoV-2 which fortunately led to manage the recent pandemic, COVID-19. According to the quite rapidly developed vaccines in a fast win...

    Authors: Mona Sadat Larijani, Delaram Doroud, Mohammad Banifazl, Afsaneh Karami, Anahita Bavand, Fatemeh Ashrafian and Amitis Ramezani
    Citation: European Journal of Medical Research 2023 28:542
  19. Aortic diseases remain a highly perilous macrovascular condition. The relationship between circulating aldosterone and aortic diseases is rarely explored, thus we investigated the difference in plasma aldoster...

    Authors: Yuting Pu, Guifang Yang, Xiaogao Pan, Yang Zhou, Aifang Zhong, Ning Ding, Yingjie Su, Wen Peng, Mengping Zeng, Tuo Guo and Xiangping Chai
    Citation: European Journal of Medical Research 2023 28:541
  20. Activating transcription factor 6 (ATF6) is an endoplasmic reticulum stress responsive gene. We previously reported that conditional knockout of hepatic ATF6 exacerbated liver metabolic damage by repressing au...

    Authors: Bingzi Dong, Ying Sun, Bingfei Cheng, Yu Xue, Wei Li and Xiaofang Sun
    Citation: European Journal of Medical Research 2023 28:540
  21. The incidence of nonhip femoral fractures is gradually increasing, but few studies have explored the risk factors for in-hospital death in patients with nonhip femoral fractures in the ICU or developed mortali...

    Authors: Zhibin Xing, Yiwen Xu, Yuxuan Wu, Xiaochen Fu, Pengfei Shen, Wenqiang Che and Jing Wang
    Citation: European Journal of Medical Research 2023 28:539
  22. During the last few decades, the increased use of various types of antibiotics in the general population caused a significant change in regional Helicobacter pylori (H. pylori) antibiotic resistance. Our aim is t...

    Authors: Haim Shmuely, Yekaterina Shvartsman, Rita Berdinstein, Jacob Yahav and Ehud Melzer
    Citation: European Journal of Medical Research 2023 28:538
  23. This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigate the use of nanotechnology in orthopedic surgery, neurosurgery, plastic surgery, surgical ...

    Authors: Farzad Abaszadeh, Muhammad Hossein Ashoub, Ghazal Khajouie and Mahnaz Amiri
    Citation: European Journal of Medical Research 2023 28:537
  24. Several clinical trials have evaluated the efficacy and safety of baricitinib in COVID-19 patients. Recently, there have been reports on critical patients, which are different from previous research results. T...

    Authors: Jing Sun, Shufang Wang, Xin Ma, Qingqing Wei, Yujuan Peng, Ying Bai, Guobin Miao, Chang Meng and Peng Liu
    Citation: European Journal of Medical Research 2023 28:536
  25. From an initial pool of 2303 studies, ten eligible and potential studies were selected through rigor inclusion and exclusion criteria for this systematic review to examine music therapy's effect on dementia. T...

    Authors: Chen Lin, He Xuanxu, Xue Yuyang, Xu Zhongqiu and Chunhai Gao
    Citation: European Journal of Medical Research 2023 28:535
  26. The association of dyslipidemia with embryo development and pregnancy outcomes is largely unknown, especially in unexplained recurrent implantation failure (uRIF) patients. Here, this study aimed to explore th...

    Authors: Yang Liu, Tianxiang Ni, Qing Zhao, Weiran Cui, Xiangxin Lan, Tingting Zhou, Qian Zhang and Junhao Yan
    Citation: European Journal of Medical Research 2023 28:534
  27. The incidence and mortality of early-onset colorectal cancer (EOCRC; < 50 years old) is increasing worldwide, with a high recurrence rate. The inherent heterogeneity of EOCRC makes its treatment challenging. H...

    Authors: Jia Yang, Yuting Zhao, Rongqiang Yuan, Yongtong Wang, Shiyi Wang, Zhiqiang Chang and Wenyuan Zhao
    Citation: European Journal of Medical Research 2023 28:533
  28. The very-long-chain fatty acid elongase (ELOVL) family plays essential roles in lipid metabolism and cellular functions. This comprehensive review explores the structural characteristics, functional properties...

    Authors: Xiangyu Wang, Hao Yu, Rong Gao, Ming Liu and Wenli Xie
    Citation: European Journal of Medical Research 2023 28:532
  29. The incidence and mortality of clear cell carcinoma of the kidney increases yearly. There are limited screening methods and advances in treating kidney renal clear cell carcinoma (KIRC). It is important to fin...

    Authors: Lv Tian, Yiming Wang, Zhiyuan Zhang, Xuechao Feng, Fengjun Xiao and Minru Zong
    Citation: European Journal of Medical Research 2023 28:531
  30. Gait impairment is common in Parkinson’s disease (PD) patients, which greatly reduces their quality of life. Executive dysfunction is associated with gait impairment. Compensatory strategies, including visual ...

    Authors: Ze-Di Hu, Shi-Guo Zhu, Jie-Fan Huang, Jin-Yu Chen, Shi-Shi Huang, Rong-Pei Liu, Zhu-Ling Chen, Lu-Lu Ma, Xiong Zhang and Jian-Yong Wang
    Citation: European Journal of Medical Research 2023 28:530
  31. Single-cell ribonucleic acid sequencing (scRNA-seq) has emerged as a transformative technology in neurological and neurosurgical research, revolutionising our comprehension of complex neurological disorders. I...

    Authors: Wireko Andrew Awuah, Arjun Ahluwalia, Shankaneel Ghosh, Sakshi Roy, Joecelyn Kirani Tan, Favour Tope Adebusoye, Tomas Ferreira, Hareesha Rishab Bharadwaj, Vallabh Shet, Mrinmoy Kundu, Amanda Leong Weng Yee, Toufik Abdul-Rahman and Oday Atallah
    Citation: European Journal of Medical Research 2023 28:529
  32. Central catheters expose ICU patients at risk of catheter-related bloodstream infections. A mechanism by which these infections occur is the contamination of the catheter during its insertion if aseptic techni...

    Authors: Nathalie van der Mee-Marquet, Anne-Sophie Valentin, Isabelle Duflot, Mathilde Farizon and Agnès Petiteau
    Citation: European Journal of Medical Research 2023 28:528
  33. COVID-19 leads to severe overwhelming inflammation in some patients mediated by various cytokines (cytokine storm) that usually leads to severe illness accompanied by cardiovascular manifestations. Growth diff...

    Authors: Sally Raafat Ishak, Mona Mostafa El Ganzoury, Eman Mahmoud Fouda, Maha Ahmad Anwar, Amany Moustafa Kamal, Heba Mostafa Hamza and Nehad Ahmed Bakry
    Citation: European Journal of Medical Research 2023 28:527
  34. Recent studies have reported associations between body mass index (BMI) and various autoimmune disorders. However, it is still uncertain whether there exists a direct cause-and-effect relationship between BMI ...

    Authors: Jinlong Huo, Yaxuan Xu, Jie Yu, Youming Guo, Xiaochi Hu, Dong Ou, Rui Qu and Lijin Zhao
    Citation: European Journal of Medical Research 2023 28:526
  35. Membranous nephropathy (MN) is a chronic glomerular disease that leads to nephrotic syndrome in adults. The aim of this study was to identify novel biomarkers and immune-related mechanisms in the progression o...

    Authors: Miaoru Han, Yi Wang, Xiaoyan Huang, Ping Li, Xing Liang, Rongrong Wang and Kun Bao
    Citation: European Journal of Medical Research 2023 28:525
  36. Although autografts are not feasible in patients with extensive burn wounds, allografts and xenografts can be used for temporary coverage. In this systematic review and meta-analysis, we compared the outcomes ...

    Authors: Rana Irilouzadian, Amirmohammad Khalaji, Hediyeh Baghsheikhi, Roham Sarmadian, Soodabeh Hoveidamanesh, Tayyeb Ghadimi and Siamak Farokh Forghani
    Citation: European Journal of Medical Research 2023 28:524
  37. The present study aims to review the existing scientific literature on the role of neutrophil to lymphocyte ratio (NLR) in diabetic peripheral neuropathy (DPN) to perform a meta-analysis on the available data.

    Authors: Armin Rezaei Shahrabi, Gabrielle Arsenault, Seyed Ali Nabipoorashrafi, Brandon Lucke-Wold, Shirin Yaghoobpoor, Fatemeh Zari Meidani, Rahem Rahmati, Arshin Ghaedi and Shokoufeh Khanzadeh
    Citation: European Journal of Medical Research 2023 28:523
  38. Trauma is the leading cause of death in the pediatric population. Although vascular trauma has an incidence of 6% in civilian population, iatrogenic injuries are the leading cause, and the most frequent injure...

    Authors: Rodrigo Lozano-Corona, Adriana Torres-Machorro, Reinhard Ortiz-Beitz, Aristeo Reyes-Monroy, Ignacio García-Lugo, Christopher Ruben-Castillo and Luis Angel Guerrero-Galindo
    Citation: European Journal of Medical Research 2023 28:521
  39. This study aims to evaluate the digitally designed ball attachment housing in its initial retentive force and after 2 years of simulated clinical use and to compare it with the regular nylon ball attachment ho...

    Authors: Hussein G. El Charkawi and Medhat Sameh Abdelaziz
    Citation: European Journal of Medical Research 2023 28:520
  40. Vascular stiffening is highly predictive of major adverse cardiovascular events. It is not clear whether microangiopathy, such as fundus arteriosclerosis, is related to carotid atherosclerosis. Hence, this stu...

    Authors: Chunxing Liu, Xiaolong Yang, Mengmeng Ji, Xiaowei Zhang, Xiyun Bian, Tingli Chen, Yihan Li, Xing Qi, Jianfeng Wu, Jing Wang and Zaixiang Tang
    Citation: European Journal of Medical Research 2023 28:518
  41. Esketamine, an N-methyl-D-aspartate receptor antagonist, is commonly used for anesthesia and analgesia clinically. It was reported to negatively regulate cell proliferation, metastasis and apoptosis in cancer cel...

    Authors: Chao Li, Jingpu Shi, Sisi Wei and Huiqun Jia
    Citation: European Journal of Medical Research 2023 28:517
  42. The epithelial–mesenchymal transition (EMT) and angiogenesis are morphogenetic processes implicated in tumor invasion and metastasis. It is found that the aberrant expression of microRNAs (miRNAs) contributes ...

    Authors: Samaneh Shojaei, Maryam Moradi-Chaleshtori, Mahdi Paryan, Ameneh Koochaki, Kazem Sharifi and Samira Mohammadi-Yeganeh
    Citation: European Journal of Medical Research 2023 28:516
  43. Aberrant glycosylation, catalyzed by the specific glycosyltransferase, is one of the dominant features of cancers. Among the glycosyltransferase subfamilies, sialyltransferases (SiaTs) are an essential part wh...

    Authors: Penglong Cao, Mingying Chen, Tianya Zhang, Qin Zheng and Mulin Liu
    Citation: European Journal of Medical Research 2023 28:515
  44. We compared hypermetabolic lymphadenopathy (HLN) on 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) after virus-vector and mRNA vaccines for coronavirus disease 2019 (COVI...

    Authors: Meng-Ting Chiang, Jann-Tay Wang, Wan-Yu Lin, Ruoh-Fang Yen, Jei-Yie Huang and Ching-Chu Lu
    Citation: European Journal of Medical Research 2023 28:513
  45. The traditional treatment of rheumatoid arthritis (RA) has some side effects. We aimed to explore the effect of metformin treatment on the expression of HMGB1, cytokines, T cell subtypes and the clinical outco...

    Authors: Lihua Zhang, Yuqing Zhou, Shengzhi Jiang, Yubei Fan, Jierou Huang, Bin Xiao, Hui Rao and Lingyun Huang
    Citation: European Journal of Medical Research 2023 28:512

    The Correction to this article has been published in European Journal of Medical Research 2023 28:598

  46. Breast cancer is the most common malignant tumor among women worldwide. GREB1L is a protein-coding gene. Previous studies have shown that GREB1L plays a vital role in lung and gastric adenocarcinoma. Currently...

    Authors: Ke Dong, Chenchen Geng, Xiaohong Zhan, Zhi Sun, Qian Pu, Peng Li, Haiyun Song, Guanghui Zhao and Haidong Gao
    Citation: European Journal of Medical Research 2023 28:510

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