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  1. VEGF facilitates tumor angiogenesis, and bevacizumab targeting VEGF is used in anti-tumor therapy. It is meaningful to clarify the upstream regulatory mechanism of VEGF. BPTF is important in chromosomal remode...

    Authors: Meng Dai, Chunyu Hua, Mingqin Wang, Li Gao, Ling Jiang and Yuan Liu
    Citation: European Journal of Medical Research 2022 27:299
  2. The optimal time point for surgical resection of synchronous colorectal liver metastases (SCLMs) is still controversial. This meta-analysis evaluated the safety and long-term prognoses of simultaneous and stag...

    Authors: Shi-hao Wang, Lei Song, Ji-yan Tang, Wei-peng Sun and Zhen Li
    Citation: European Journal of Medical Research 2022 27:297
  3. The inhibitory activities of vitamins K2 against clinical isolates of quinolone-resistant and methicillin-resistant Staphylococcus aureus (QR-MRSA) are unclear. The main aim is to better understand of inhibitory ...

    Authors: Naime Kashefi Pasandideh, Hamed Tahmasebi, Sanaz Dehbashi, Behrouz zeyni and Mohammad Reza Arabestani
    Citation: European Journal of Medical Research 2022 27:295

    The Correction to this article has been published in European Journal of Medical Research 2023 28:66

  4. Early identifying sepsis patients who had higher risk of poor prognosis was extremely important. The aim of this study was to develop an artificial neural networks (ANN) model for early predicting clinical out...

    Authors: Yingjie Su, Cuirong Guo, Shifang Zhou, Changluo Li and Ning Ding
    Citation: European Journal of Medical Research 2022 27:294
  5. Tumor immune microenvironment (TIME) plays a vital role in breast cancer development, treatment resistance, and prognosis. This study evaluates the association of TIME profiling and 21-gene recurrence score (R...

    Authors: Yiwei Tong, Jiahui Huang, Weili Ren, Jing Yu, Xu Zhang, Zheng Wang, Jin Hong, Weiqi Gao, Jiayi Wu, Min Ji, Kunwei Shen and Xiaosong Chen
    Citation: European Journal of Medical Research 2022 27:293
  6. Endometrial carcinoma (EC) is one of the most common female reproductive system tumors, which seriously threatens women's health. This preliminary study aimed to investigate the effects of quercetin on the EC ...

    Authors: Xiaoqin Li, Qianqian Zhu, Meng Ma and Haiyan Guo
    Citation: European Journal of Medical Research 2022 27:292
  7. The emergence of new variants of SARS-CoV-2 is continuously posing pressure to the epidemic prevention and control in China. The Omicron variant of SARS-CoV-2 having stronger infectivity, immune escape ability...

    Authors: Peiyan Zhang, Zhao Cai, Zhiguang He, Peifen Chen, Weibo Wu, Yuanlong Lin, Shiyan Feng, Ling Peng, Jianming Li, Jing Yuan, Liang Yang, Fuxiang Wang, Yingxia Liu and Hongzhou Lu
    Citation: European Journal of Medical Research 2022 27:291
  8. Ventricular premature complex (VPC) is a common arrhythmia in clinical practice. VPC could trigger ventricular tachycardia/fibrillation or VPC-induced cardiomyopathy in susceptible patients. Existing screening...

    Authors: Sheng-Nan Chang, Yu-Heng Tseng, Jien-Jiun Chen, Fu-Chun Chiu, Chin-Feng Tsai, Juey-Jen Hwang, Yi-Chih Wang and Chia-Ti Tsai
    Citation: European Journal of Medical Research 2022 27:289
  9. Osteoarthritis (OA) is a common chronic disabling disease that affects hundreds of millions of people around the world. The most important pathological feature is the rupture and loss of articular cartilage, a...

    Authors: Hanhan Guo, Jianghong Huang, Yujie Liang, Daping Wang and Huawei Zhang
    Citation: European Journal of Medical Research 2022 27:288
  10. Helical tomotherapy (HT) is a viable method for delivering total body irradiation (TBI) when preparing patients for allogenic stem cell or bone-marrow transplantation. TBI can be planned to reduce the amount o...

    Authors: Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Frank A. Giordano, Georgios Chatzikonstantinou and Leonard C. Schmeel
    Citation: European Journal of Medical Research 2022 27:287
  11. Congenital heart defects (CHDs) are the most common congenital malformations, including structural malformations in the heart and great vessels. CHD complications such as low birth weight, prematurity, pregnan...

    Authors: Avisa Tabib, Taravat Talebi, Serwa Ghasemi, Maryam Pourirahim, Niloofar Naderi, Majid Maleki and Samira Kalayinia
    Citation: European Journal of Medical Research 2022 27:286
  12. The effects of diastolic arterial pressure (DAP) and heart rate (HR) on the prognosis of patients with septic shock are unclear, and whether these effects persist over time is unknown. We aimed to investigate ...

    Authors: Wenyan Xiao, Wanjun Liu, Jin Zhang, Yu Liu, Tianfeng Hua and Min Yang
    Citation: European Journal of Medical Research 2022 27:285
  13. Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. It is known that AIH originates not from the spleen but from the liver itself. Nonetheless, most details of the etiology and ...

    Authors: Janine Dywicki, Laura Elisa Buitrago-Molina, Fatih Noyan, Jerome Schlue, Konstantinos Iordanidis, Michael P. Manns, Heiner Wedemeyer, Elmar Jaeckel and Matthias Hardtke-Wolenski
    Citation: European Journal of Medical Research 2022 27:284
  14. Under the obvious acetabular superolateral bone defect of Crowe II/III hips, this study aimed to investigate the difference in surgical technique of different hip center positions from the surgical data and cl...

    Authors: Cheng-Qi Jia, Hong-Fa Pan, Yu-Jie Wu, Yong-Gang You, Shi-Qi Cao and Xue-Song Zhang
    Citation: European Journal of Medical Research 2022 27:282
  15. To detect the changes in Nel-like 2 (NELL2) in cerebrospinal fluid (CSF) in the outcome of tuberculous meningitis (TBM) patients and to initially evaluate its potential as a marker.

    Authors: Jianhua Chen, Jie Wu, Yong Luo and Nanqu Huang
    Citation: European Journal of Medical Research 2022 27:281
  16. Hepatic resection is a potentially curative treatment for patients with hepatocellular carcinoma (HCC). The treatment of elderly patients with HCC has always been difficult. With the development of geriatrics ...

    Authors: Lining Xu, Yingying Xu, Guiping Li and Bo Yang
    Citation: European Journal of Medical Research 2022 27:280
  17. Hospitalized patients with non-severe community-acquired pneumonia (CAP) are treated with a β-lactam plus either a macrolide or doxycycline. Limited data exist on the effectiveness of the latter combination. T...

    Authors: Raghad K. Aldhahri, Shahad G. Gabb, Ohoud A. Shoaib, Reem M. Almadani, Khalid Eljaaly and Abrar K. Thabit
    Citation: European Journal of Medical Research 2022 27:279
  18. Most of hepatocellular carcinoma (HCC) arises on the background of chronic inflammation. The presence of infiltrating inflammatory cells is associated with tumour initiation, progression and clinical response ...

    Authors: Guo-Qiang Pan, Chun-Cheng Yang, Xiao-ling Shang, Zhao-Ru Dong and Tao Li
    Citation: European Journal of Medical Research 2022 27:278
  19. Preoperative evaluation of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is important for surgical strategy determination. We aimed to develop and establish a preoperative predic...

    Authors: Yijie Hao, Qingxia Yang, Qiye He, Huanjing Hu, Zongpeng Weng, Zhixi Su, Shuling Chen, Sui Peng, Ming Kuang, Zhihang Chen and Lixia Xu
    Citation: European Journal of Medical Research 2022 27:276
  20. Heme oxygenase one (HO-1) is considered a poor prognostic factor for survival in patients with severe-to-critical coronavirus disease (COVID-19), but the clinical correlation between heme catabolism biomarkers...

    Authors: Hsin-Yi Chen, I-Shiang Tzeng, Kuo-Wang Tsai, Yao-Kuang Wu, Ching-Feng Cheng, Kuo-Cheng Lu, Hsueh-Wen Chung, You-Chen Chao and Wen-Lin Su
    Citation: European Journal of Medical Research 2022 27:275
  21. The combined application of blue dye and radioisotopes is currently the primary mapping technique used for sentinel lymph node biopsy (SLNB) in breast cancer patients. However, radiocolloid techniques have not...

    Authors: Baiye Wang, Caifeng Ou, Jingang Yu, Jianping Ye, Yunfeng Luo, Yu Wang and Pusheng Zhang
    Citation: European Journal of Medical Research 2022 27:274
  22. Increasing evidence suggests that glucagon-like peptide 1 (GLP-1) receptor agonists (RA) can stabilize glycemic variability (GV) and interfere with eating behavior. This study compared the impact of insulin, G...

    Authors: Yi-Hsuan Lin, Chia-Hung Lin, Yu-Yao Huang, Hsin-Yun Chen, An-Shun Tai, Shih-Chen Fu, Sheng-Hwu Hsieh, Jui-Hung Sun, Szu-Tah Chen and Sheng-Hsuan Lin
    Citation: European Journal of Medical Research 2022 27:273
  23. Distant metastasis, which occurs at a rate of 25% in patients with esophageal cancer (EC), has a poor prognosis, with previous studies reporting an overall survival of only 3–10 months. However, few studies ha...

    Authors: Chao Zhu, Fengchun Mu, Songping Wang, Qingtao Qiu, Shuai Wang and Linlin Wang
    Citation: European Journal of Medical Research 2022 27:272
  24. Breast cancer is a worldwide health concern, and surgical removal has remained the preferred therapeutic option in most patients. Furthermore, the current study was designed to investigate the disease-free sur...

    Authors: Mohammad Yasin Karami, Laleh Dehghanpisheh, Ali Karami, Zahra Sabzloun, Hamid Reza Niazkar, Najmeh Mojarad, Ashkan Panah, Abdolrasoul Talei and Sedigheh Tahmasebi
    Citation: European Journal of Medical Research 2022 27:271
  25. The surgical treatment of inferior patellar pole fractures can be a challenge, especially in geriatric patients, who are particularly frequently affected by osteoporosis. The objective of this biomechanical st...

    Authors: Jana Seggewiss, Luis Fernando Nicolini, Philipp Lichte, Johannes Greven, Marx Ribeiro, Andreas Prescher, Roman Michalik, Christian Herren, Philipp Kobbe, Frank Hildebrand and Miguel Pishnamaz
    Citation: European Journal of Medical Research 2022 27:270
  26. The management of acute respiratory failure during pregnancy is a poorly defined issue in the literature, especially regarding the use of the prone position and the appropriate time for delivery. This study de...

    Authors: Rodrigo Nacif Barbosa, Maria Aparecida Braga, Bárbara Braga Costa and Frederico José Amedee Peret
    Citation: European Journal of Medical Research 2022 27:269
  27. Leptospirosis is an emerging neglected zoonotic disease that presents with nonspecific signs/symptoms and it can be mistaken for other diseases. Owing to limited diagnostic capacity and unawareness, the data o...

    Authors: Derick Hope, Stephen Businge, Stella Kyoyagala and Joel Bazira
    Citation: European Journal of Medical Research 2022 27:268
  28. Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture. To reduce this risk, the aim of this study was to compare the combination e...

    Authors: Dalia M. Badary, Heba A. Galal, Mahmoud H. Abdelraheim, Mohamed I. Sedeek, Nesma M. Mohamed, Zakaria Y. Abd Elmageed and Magda M. Y. Farrag
    Citation: European Journal of Medical Research 2022 27:267
  29. Massage is widely used as a traditional technique during labor and delivery. The aim of this study was to evaluate the effect of Swedish massage with and without chamomile oil on delivery outcomes.

    Authors: Fatemeh Eskandari, Parvaneh Mousavi, Mahboubeh Valiani, Saeed Ghanbari and Mina Iravani
    Citation: European Journal of Medical Research 2022 27:266
  30. Helical TomoTherapy® is widely used for total body irradiation as a component of conditioning regimens before allogeneic bone-marrow transplantation. However, this technique limits the maximum length of a plannin...

    Authors: Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano
    Citation: European Journal of Medical Research 2022 27:265
  31. Hepatic encephalopathy (HE) is a reversible syndrome of brain dysfunction caused by advanced liver disease. Weighted gene co-expression network analysis (WGCNA) could establish a robust co-expression network t...

    Authors: Chihao Zhang, Guqing Luo, Jiayun Lin, Zhifeng Zhao, Meng Luo and Hongjie Li
    Citation: European Journal of Medical Research 2022 27:264
  32. The poor prognosis of cervical spine surgery is mainly manifested as poor neurological recovery and the presence of new upper extremity dysfunction that promotes significant psychological and physiological bur...

    Authors: Peng Wang, Baoge Liu, Tianhua Rong and Bingxuan Wu
    Citation: European Journal of Medical Research 2022 27:263
  33. Soluble Klotho (S-Klotho) is an anti-aging protein mainly secreted by the kidneys. Hyperuricemia is prevalent among middle-aged and elderly individuals, which affects the development of various chronic disease...

    Authors: Haitao Xie, Ning Li, Guowei Zhou, Qian Liu, Haiyan Wang, Jie Han, Le Shen, Peng Yu, Jiandong Chen and Xiaohu Chen
    Citation: European Journal of Medical Research 2022 27:262
  34. At present, the relationship between serum homocysteine (Hcy), fibrinogen (FIB), lipoprotein-a (LPa), and PAD is uncertain, and there has been no meta-analysis to establish the dose–response relationship betwe...

    Authors: Hecheng Wang, Pengpeng Wu, Deying Jiang, Hao Zhang, Jian Zhang, Yu Zong and Yanshuo Han
    Citation: European Journal of Medical Research 2022 27:261
  35. Serum uric acid (SUA) acts as an antioxidant and abnormally low SUA may raise the risk of developing atherosclerotic disorders. There is a U-shaped association between SUA with cardiovascular diseases (CVDs) i...

    Authors: Yao-Wei Zou, Qian-Hua Li, Ying-Ying Zhu, Jie Pan, Jing-Wei Gao, Jian-Zi Lin, Tao Wu, Qian Zhang, Hu-Wei Zheng, Ying-Qian Mo, Jian-Da Ma and Lie Dai
    Citation: European Journal of Medical Research 2022 27:260
  36. Aberrant DNA methylation plays a crucial role in the progression of myeloid neoplasms. Previously, our literature reported that slit guidance ligand 2 (SLIT2) promoter methylation was associated with disease prog...

    Authors: De-long Wu, Yun Wang, Ting-juan Zhang, Ming-qiang Chu, Zi-jun Xu, Qian Yuan, Ji-chun Ma, Jiang Lin, Jun Qian and Jing-dong Zhou
    Citation: European Journal of Medical Research 2022 27:259
  37. Adequate sedation is essential for pediatric patients undergoing 3Tesla (T) magnetic resonance imaging (MRI). Using propofol alone is associated with patient arousing and adverse airway events. This study aime...

    Authors: Shang-xian Xu, Xi-sheng Shan, Jin-meng Gao, Hua-xian Liu, Wei-rong Chen, Shan-shan Gao, Fu-hai Ji, Ke Peng and Qian Wang
    Citation: European Journal of Medical Research 2022 27:258
  38. Hair graying, a prototypical sign of human aging, is a progressive loss of pigmentation from growing hair shafts caused by disease and as a side effect of medications. Cerebrolysin is a neuropeptide preparatio...

    Authors: Gustavo Villarreal-Reyna, Rodolfo Garza-Morales, Adolfo Soto-Domínguez, Lorena Montañez-Guerrero, Odila Saucedo-Cárdenas, Minerva Gómez-Flores, Jorge Alejandro Ocampo-Garza, José Juan Pérez-Trujillo and Roberto Montes-de-Oca-Luna
    Citation: European Journal of Medical Research 2022 27:257
  39. Despite the wide clinical application of checkpoint inhibitor immunotherapy in lung adenocarcinoma, its limited benefit to patients remains puzzling to researchers. One of the mechanisms of immunotherapy resis...

    Authors: Song Qiu, Ying Wang, Hui Rao, Qiuyang Que, Yanyang Wu, Rui Zhu, Xiaofei Feng, Jun Chi, Weiling Lai, Yihang Sun, Qi Xiao, Huaqiu Shi and Yi Xiang
    Citation: European Journal of Medical Research 2022 27:256
  40. The presentation of peptides and the subsequent immune response depend on the MHC characteristics and influence the specificity of the immune response. Several studies have found an association between HLA var...

    Authors: Johannes C. Fischer, Vera Balz, Danny Jazmati, Edwin Bölke, Noemi F. Freise, Verena Keitel, Torsten Feldt, Björn-Erik Ole Jensen, Johannes Bode, Tom Lüdde, Dieter Häussinger, Ortwin Adams, E. Marion Schneider, Jürgen Enczmann, Jutta M. Rox, Derik Hermsen…
    Citation: European Journal of Medical Research 2022 27:255
  41. Traumatic brain injury (TBI) causes mortality and long-term disability among young adults and imposes a notable cost on the healthcare system. In addition to the first physical hit, secondary injury, which is ...

    Authors: Nafiseh Gharizadeh, Morteza Ghojazadeh, Amirreza Naseri, Sanam Dolati, Faezeh Tarighat and Hassan Soleimanpour
    Citation: European Journal of Medical Research 2022 27:254
  42. Our goal was to examine the therapeutic effect of a self-designed digital six-axis external fixator technique for the correction of severe lower extremity deformities.

    Authors: Yufeng Lu, Jinfeng Li, Feng Qiao, Zhaochen Xu, Baogang Zhang, Bin Jia, Jinlong He, Liang Qi, Min Wang, Chen Fei and Xiaoming Cao
    Citation: European Journal of Medical Research 2022 27:252
  43. Patients with non-alcoholic fatty liver disease (NAFLD) may be more susceptible to coronavirus disease 2019 (COVID-19) and even more likely to suffer from severe COVID-19. Whether there is a common molecular p...

    Authors: Shi-Tao Jiang, Yao-Ge Liu, Lei Zhang, Xin-Ting Sang, Yi-Yao Xu and Xin Lu
    Citation: European Journal of Medical Research 2022 27:251
  44. Many women experience menstruation-related health issues during their child-bearing years. This study aimed to evaluate women’s tendency to seek Traditional Chinese Medicine (TCM) and/or Western Medicine (WM) ...

    Authors: Jong-Long Guo, Tzu-Chi Lee, Fen-He Lin, Hsiao-Pei Hsu and Chiu-Mieh Huang
    Citation: European Journal of Medical Research 2022 27:250

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