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  1. Inadequate activation of the innate immune system after trauma can lead to severe complications such as Acute Respiratory Distress Syndrome and Multiple Organ Dysfunction Syndrome. The spleen is thought to mod...

    Authors: Michel Paul Johan Teuben, Arne Hollman, Taco Blokhuis, Roman Pfeifer, Roy Spijkerman, Henrik Teuber, Hans-Christoph Pape and Luke Petrus Hendrikus Leenen
    Citation: European Journal of Medical Research 2021 26:26
  2. The incidence of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament reconstruction (ACLR) is high, but there is still a lack of intra-operative preventive measures. This study aimed to evalu...

    Authors: Xinghui Liu, Rong Chen, Liangbo Jiang, Xiangwei Li and Zhibo Sun
    Citation: European Journal of Medical Research 2021 26:24
  3. Lung cancer is the fourth most common form of the tumor spreading to the bone. Among all patients of lung carcinoma, the most common sites of bone metastasis are vertebrae, ribs, and pelvis. By comparison, the...

    Authors: Karl Wu and Yu-Hao Huang
    Citation: European Journal of Medical Research 2021 26:23
  4. Citation analysis has been increasingly applied to assess the quantity and quality of scientific research in various fields worldwide. However, these analyses on spinal surgery do not provide visualization of ...

    Authors: Po-Hsin Chou, Yu-Tsen Yeh, Wei-Chih Kan, Tsair-Wei Chien and Shu-Chun Kuo
    Citation: European Journal of Medical Research 2021 26:22
  5. Clubfeet and constriction band syndrome is a very rare non-idiopathic condition. Treatment is often difficult and the recurrence deformity rate is high. The purpose of this study was to assess the effectivenes...

    Authors: Bujar Shabani, Dafina Bytyqi and Cen Bytyqi
    Citation: European Journal of Medical Research 2021 26:21
  6. Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dos...

    Authors: Saeidreza JamaliMoghadamSiahkali, Besharat Zarezade, Sogol Koolaji, SeyedAhmad SeyedAlinaghi, Abolfazl Zendehdel, Mohammad Tabarestani, Ehsan Sekhavati Moghadam, Ladan Abbasian, Seyed Ali Dehghan Manshadi, Mohamadreza Salehi, Malihe Hasannezhad, Sara Ghaderkhani, Mohsen Meidani, Faeze Salahshour, Fatemeh Jafari, Navid Manafi…
    Citation: European Journal of Medical Research 2021 26:20
  7. Diaphragmatic lesions as a result of blunt or penetrating trauma are challenging to detect in the initial trauma setting. This is especially true when diaphragmatic trauma is part of a polytrauma. Complication...

    Authors: Morris Beshay, Martin Krüger, Kashika Singh, Rainer Borgstedt, Tahar Benhidjeb, Edwin Bölke, Thomas Vordemvenne and Jan Schulte am Esch
    Citation: European Journal of Medical Research 2021 26:19
  8. Patients with severe COVID-19 have disorders of the respiratory, cardiovascular, coagulation, skeletal muscle, and central nervous systems. These systemic failures may be associated with cytokine release syndr...

    Authors: Nobutaka Chiba, Masakazu Matsuzaki, Takayuki Mawatari, Minori Mizuochi, Atsushi Sakurai and Kosaku Kinoshita
    Citation: European Journal of Medical Research 2021 26:18
  9. Ultrasonic measurement has not been utilized to assess the functional recovery of transplanted muscle. This study aimed to investigate the feasibility of using B-ultrasound measurement to assess muscle recover...

    Authors: Yi Hou, Jiantao Yang, Bengang Qin, Liqiang Gu and Jia Zheng
    Citation: European Journal of Medical Research 2021 26:17
  10. Hypothermic machine perfusion (HMP) improves the quality of donor livers for transplantation, both in animal models and in clinical practice. Treatment with SP600125, an inhibitor of c-Jun N-terminal kinase (J...

    Authors: Yijie Zhang, Qi Pan, Ying Cheng and Yongfeng Liu
    Citation: European Journal of Medical Research 2021 26:15
  11. Absence of cortical alignment in wedge-shaped and multifragmentary fractures (Fx) results in decreased fixation stability. The aim of this study was to compare the outcome using 2.0- vs. 3.5-mm screws for open...

    Authors: M. Wurm, M. Zyskowski, F. Greve, A. Gersing, P. Biberthaler and C. Kirchhoff
    Citation: European Journal of Medical Research 2021 26:14
  12. Here, we report an atypical HIV-vacuolar myelopathy and search the available medical literature about atypical presentations of human immunodeficiency virus associate vacuolar myelopathy (HIV-VM) and immunoglo...

    Authors: Tau Mongezi, Joseph Sibi, George Jerry, Ibañez-Valdés Lourdes de Fátima, Dubula Tozama and Foyaca Sibat Humberto
    Citation: European Journal of Medical Research 2021 26:13
  13. Endometriosis is associated with a high number of chronic pelvic pain and reduced quality of life. Colorectal resections in case of bowel involvement of endometriosis are associated with an unneglectable morbi...

    Authors: Peter Tschann, Nikola Vitlarov, Martin Hufschmidt, Daniel Lechner, Paolo N. C. Girotti, Felix Offner, Burghard Abendstein and Ingmar Königsrainer
    Citation: European Journal of Medical Research 2021 26:12
  14. Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used in severely injured patients with uncontrollable bleeding. However, zone-dependent effects of REBOA are rarely described. We compar...

    Authors: Sascha Halvachizadeh, Ladislav Mica, Yannik Kalbas, Miriam Lipiski, Marko Canic, Michel Teuben, Nikola Cesarovic, Zoran Rancic, Paolo Cinelli, Valentin Neuhaus, Hans- Christoph Pape and Roman Pfeifer
    Citation: European Journal of Medical Research 2021 26:10
  15. This study attempts to evaluate the prognostic role of PHYH for overall survival (OS) in clear cell renal cell carcinoma (ccRCC) by means of publicly available data from The Cancer Genome Atlas (TCGA). Clinica...

    Authors: Qiu Zhengqi, Guo Zezhi, Jiang Lei, Qiu He, Pan Jinyao and Ao Ying
    Citation: European Journal of Medical Research 2021 26:9
  16. More and more studies have confirmed that miRNAs play an important role in maintaining bone remodeling and bone metabolism. This study investigated the expression level of miR-206 in the serum of osteoporosis ...

    Authors: Zhiyuan Lu, Dawei Wang, Xuming Wang, Jilong Zou, Jiabing Sun and Zhenggang Bi
    Citation: European Journal of Medical Research 2021 26:8
  17. The aim of this study was to detect the expression of interleukin (IL)-1β and transforming growth factor (TGF)-β1 in the colonic tissue and serum of irritable bowel syndrome (IBS) rats, as well as the distribu...

    Authors: Guanqun Chao, Zhaojun Wang, Xinli Chen and Shuo Zhang
    Citation: European Journal of Medical Research 2021 26:7
  18. Rodent models of liver resection have been used to investigate and evaluate the liver’s complex physiology and pathology since 1931. First documented by Higgins and Anderson, such models were created to unders...

    Authors: Can Kamali, Kaan Kamali, Philipp Brunnbauer, Katrin Splith, Johann Pratschke, Moritz Schmelzle and Felix Krenzien
    Citation: European Journal of Medical Research 2021 26:6
  19. Unproven stem cell treatments may involve serious health, personal, and financial considerations. Due to worldwide spread, illegal stem cell therapies have become a major public health problem. We have already...

    Authors: Željka Večerić-Haler, Špela Borštnar, Boštjan Luzar, Maja Jerše and Nika Kojc
    Citation: European Journal of Medical Research 2021 26:5
  20. Intravenous opioids are administered for the management of visceral pain after laparoscopic surgery. Whether oxycodone has advantages over other opioids in the treatment of visceral pain is not yet clear.

    Authors: Yan Li, Zhi Dou, Liqiang Yang, Qi Wang, Jiaxiang Ni and Jun Ma
    Citation: European Journal of Medical Research 2021 26:4

    The Correction to this article has been published in European Journal of Medical Research 2021 26:16

  21. Current evidence regarding the prognostic relevance of urinary sodium-to-potassium ratio (Na-to-K ratio), as an indicator of diet quality is limited. This study was conducted to investigate whether urinary Na-...

    Authors: Parvin Mirmiran, Zahra Gaeini, Zahra Bahadoran, Asghar Ghasemi, Reza Norouzirad, Maryam Tohidi and Fereidoun Azizi
    Citation: European Journal of Medical Research 2021 26:3
  22. Despite the significant reductions in under-five mortality, campylobacteriosis has emerged as one of the most common causative agents of bacterial foodborne gastroenteritis in humans. We performed this systema...

    Authors: Kuma Diriba, Ephrem Awulachew and Asrat Anja
    Citation: European Journal of Medical Research 2021 26:2
  23. Critical-sized bone defects, mainly from trauma, infection or tumor resection are a challenging condition, often resulting in prolonged, complicated course of treatment. Autografts are considered as the gold s...

    Authors: Philipp Kobbe, Markus Laubach, Dietmar W. Hutmacher, Hatem Alabdulrahman, Richard M. Sellei and Frank Hildebrand
    Citation: European Journal of Medical Research 2020 25:70
  24. The success of conversion total hip arthroplasty (THA) among primary THA and revision THA remains unclear. We hypothesized that most conversion THA’s can be performed using primar...

    Authors: Soufiane Aharram, Mounir Yahyaoui, Jawad Amghar, Abdelkarim Daoudi and Omar Agoumi
    Citation: European Journal of Medical Research 2020 25:69
  25. The number of patients undergoing flexible ureterenoscopy (FURS) for the treatment of kidney stones (renal calculi) is increasing annually, and as such the development of post-operative complications, such as ...

    Authors: Stephen Fôn Hughes, Alyson Jayne Moyes, Rebecca May Lamb, Peter Ella-tongwiis, Nana Yaa Frempomaa Snyper and Iqbal Shergill
    Citation: European Journal of Medical Research 2020 25:68
  26. The recently described ‘critical trochanter angle’ (CTA) is a novel parameter in the preoperative risk assessment of stem malalignment in total hip arthroplasty. As its reproducibility needs to be evaluated, t...

    Authors: Sebastian Serong, Moritz Schutzbach, Ivica Zovko, Marcus Jäger, Stefan Landgraeber and Marcel Haversath
    Citation: European Journal of Medical Research 2020 25:67
  27. Although distal radius fractures (DRFs) are clinically common, intra-articular DRFs accompanied by dorsally displaced free fragments are much less so. At present, it is very difficult to fix and stabilize the ...

    Authors: Zhaofeng Jia, Shijin Wang, Wei Jiang, Chuangli Li, Jiandong Lin, Qisong Liu, Guangheng Li and Xinjia Hu
    Citation: European Journal of Medical Research 2020 25:66
  28. Tuberculosis (TB) is a major health problem worldwide. Even in highly prevalent countries, primary gastroduodenal tuberculosis is a rare manifestation of extrapulmonary tuberculosis. In recent years, as the in...

    Authors: Yuanhua Li, Suhuan Liao, Haijun Zuo, Wei Yang and Di Jiang
    Citation: European Journal of Medical Research 2020 25:65
  29. Obesity has been widely reported to be associated with the disease progression of coronavirus disease 2019 (COVID-19); however, some studies have reported different findings. We conducted a systematic review a...

    Authors: Yanan Chu, Jinxiu Yang, Jiaran Shi, Pingping Zhang and Xingxiang Wang
    Citation: European Journal of Medical Research 2020 25:64
  30. Local tissue damage caused by electrical burns is often deep and severe. High-voltage electrical burns are common in the head, neck and torso areas. These are mostly caused by direct contact with the power sup...

    Authors: Chengying Meng, Yuyao Liu, Huan Wang, Youjun Sun, Shiping Lu, Yan Zhou, Jiayan Hu, Youxin Yu, Linsen Fang, Yexiang Sun and Delin Hu
    Citation: European Journal of Medical Research 2020 25:63
  31. In the stabilization of femoral fractures in mono- and polytrauma, clinical practice has shown better care through intramedullary nailing. However, the reason why this is the case is not fully understood. In a...

    Authors: Johannes Greven, Klemens Horst, Zhi Qiao, Felix Marius Bläsius, Ümit Mert, Michel Paul Johan Teuben, Nils Hendrik Becker, Roman Pfeifer, Hans-Christoph Pape and Frank Hildebrand
    Citation: European Journal of Medical Research 2020 25:62
  32. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged from China in December 2019 and has presented as a substantial and serious threat to global health. We aimed to describe the clinical, epide...

    Authors: Abbas Al Mutair, Saad Alhumaid, Waad N. Alhuqbani, Abdul Rehman Z. Zaidi, Safug Alkoraisi, Maha F. Al-Subaie, Alanoud M. AlHindi, Ahmed K. Abogosh, Aljwhara K. Alrasheed, Aya A. Alsharafi, Mohammed N. Alhuqbani, Njoud A. Alhowar, Samer Salih, Mogbil A. Alhedaithy, Jaffar A. Al-Tawfiq, Haifa Al-Shammari…
    Citation: European Journal of Medical Research 2020 25:61
  33. Hyaluronic acid (hyaluronan; HA) is an essential component of the extracellular matrix (ECM) of the skin. The HA-degrading enzyme hyaluronidase (HYAL) is critically involved in the HA-metabolism. Yet, only lit...

    Authors: Bettina Alexandra Buhren, Holger Schrumpf, Katharina Gorges, Oliver Reiners, Edwin Bölke, Jens W. Fischer, Bernhard Homey and Peter Arne Gerber
    Citation: European Journal of Medical Research 2020 25:60
  34. Dosing recommendations for the treatment of pregnancy-acquired toxoplasmosis are empirical and widely based on experimental data. There are no pharmacological data on pregnant women with acute Toxoplasma gondii i...

    Authors: Ingrid Reiter-Owona, Harald Hlobil, Martin Enders, Ute Klarmann-Schulz, Barbara Gruetzmacher, Veronika Rilling, Achim Hoerauf and Justus G. Garweg
    Citation: European Journal of Medical Research 2020 25:59
  35. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Kai Xia, Wentian Sun, Liyuan Yu, Xinqi Huang, Zhihe Zhao and Jun Liu
    Citation: European Journal of Medical Research 2020 25:58

    The original article was published in European Journal of Medical Research 2020 25:50

  36. This article reports a patient who survived severe pneumonia, pyopneumothorax with acute respiratory distress syndrome (ARDS), and septic shock, which is very difficult to treat.

    Authors: Xi Wang, Jian Lan, Ruijie Zhang and Xiaoqing Luo
    Citation: European Journal of Medical Research 2020 25:57
  37. This study aimed to assess the impact of 15 days before, 15 days during, and 15 days after the lockdown on the trends in the prevalence and mortality in 27 countries during COVID-19 pandemic.

    Authors: Sultan Ayoub Meo, Abdulelah Adnan Abukhalaf, Ali Abdullah Alomar, Faris Jamal AlMutairi, Adnan Mahmood Usmani and David C. Klonoff
    Citation: European Journal of Medical Research 2020 25:56
  38. Chylothorax is a rare complication of pediatric cardiac operations that occurs more frequently in children with Noonan syndrome, a genetic disorder associated with cardiac defects and lymphatic anomalies.

    Authors: Kay T. Pham, Duraisamy Balaguru, Varaha S. Tammisetti, Carlos J. Guevara, John C. Rasmussen, Rodrick C. Zvavanjanja, Robert Hanfland, Eva M. Sevick-Muraca and Melissa B. Aldrich
    Citation: European Journal of Medical Research 2020 25:55
  39. The novel coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is leading to a worldwide pandemic. Except representative manifestation of pne...

    Authors: Zeng-hong Wu and Dong‑liang Yang
    Citation: European Journal of Medical Research 2020 25:54
  40. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Johannes C. Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach, Stefanie Corradini, Ute Ganswindt, Dieter Häussinger, Torsten Feldt, Hubert Schelzig, Hans Bojar…
    Citation: European Journal of Medical Research 2020 25:53

    The original article was published in European Journal of Medical Research 2020 25:16

  41. Periprosthetic fibroblast-like cells (PPFs) play an important role in aseptic loosening of arthroplasties. Various studies have examined PPF behavior in monolayer culture systems. However, the periprosthetic t...

    Authors: Eliza S. Hartmann, Sabine Schluessel, Miriam I. Köhler, Felicitas Beck, Julia I. Redeker, Burkhard Summer, Veronika Schönitzer, Andreas Fottner and Susanne Mayer-Wagner
    Citation: European Journal of Medical Research 2020 25:52
  42. The purpose of this study was to observe the effect of hematoporphyrin monomethyl ether (HMME)-mediated low-frequency and low-intensity ultrasound on mature and stable Staphylococcus aureus (S. aureus) biofilms u...

    Authors: Tao Wang, Wei Ma, Zhinan Jiang and Liangjia Bi
    Citation: European Journal of Medical Research 2020 25:51
  43. Mandibular deviations are common clinical complaints. The orthodontic or orthognathic treatment of mandibular deviations is tricky because a comprehensive diagnosis, especially a functional one, is difficult t...

    Authors: Kai Xia, Wentian Sun, Liyuan Yu, Xinqi Huang, Zhihe Zhao and Jun Liu
    Citation: European Journal of Medical Research 2020 25:50

    The Correction to this article has been published in European Journal of Medical Research 2020 25:58

  44. The coronavirus disease 2019 (COVID-19) has brought a global disaster. Quantitative lesions may provide the radiological evidence of the severity of pneumonia and further to assess the effect of comorbidity on...

    Authors: Cui Zhang, Guangzhao Yang, Chunxian Cai, Zhihua Xu, Hai Wu, Youmin Guo, Zongyu Xie, Hengfeng Shi, Guohua Cheng and Jian Wang
    Citation: European Journal of Medical Research 2020 25:49
  45. Coagulase-negative staphylococcus (CoNS) is considered to be the major reservoirs for genes facilitating the evolution of S. aureus as a successful pathogen. The present study aimed to determine the occurrence of...

    Authors: Mona Nasaj, Zahra Saeidi, Hamed Tahmasebi, Sanaz Dehbashi and Mohammad Reza Arabestani
    Citation: European Journal of Medical Research 2020 25:48
  46. Heart failure is a syndrome with increasing prevalence in concordance with the aging population and better survival rates from myocardial infarction. Morbidity and mortality are high in chronic heart failure p...

    Authors: Thomas Vollmert, Martin Hellmich, Natig Gassanov, Fikret Er, Seyrani Yücel, Erland Erdmann and Evren Caglayan
    Citation: European Journal of Medical Research 2020 25:47
  47. Emerging evidence indicates that an elevated C-reactive protein-to-albumin ratio (CAR) may be associated with a poor prognosis in pancreatic ductal adenocarcinoma (PDAC). Further evidence showing that this rat...

    Authors: Laura van Wijk, Guus W. de Klein, Matthijs A. Kanters, Gijs A. Patijn and Joost M. Klaase
    Citation: European Journal of Medical Research 2020 25:46

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