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  1. Acute kidney injury (AKI) is a common and serious complication of cardiac surgery and is associated with increased mortality and morbidity, accompanied by a substantial economic burden. The pathogenesis of car...

    Authors: Ying Yu, Chenning Li, Shuainan Zhu, Lin Jin, Yan Hu, Xiaomin Ling, Changhong Miao and Kefang Guo
    Citation: European Journal of Medical Research 2023 28:45
  2. Although increased production of malondialdehyde (MDA), an end product of lipid oxidation caused by reactive oxygen species (ROS), has been found be elevated in hypertensive population, whether MDA contributed...

    Authors: Ying Huang, Hong Chen, Qifan Liu, Jinzhu Hu, Dongxi Hu, Zixi Huang, Zhenyan Xu and Rong Wan
    Citation: European Journal of Medical Research 2023 28:44
  3. There are limited data about nosocomial coinfections of COVID-19 cases monitored in the intensive care unit. This study aims to investigate coinfections in COVID-19 patients followed in an intensive care unit ...

    Authors: Banu Karaca, Murat Aksun, Nagihan Altıncı Karahan, Senem Girgin, Bahar Ormen, Ahmet Salih Tuzen, Tuna Demirdal and Atilla Sencan
    Citation: European Journal of Medical Research 2023 28:43
  4. Persistent infection with high-risk Human papillomaviruses (HPV), such as hr-HPV-16 and hr-HPV-18, lead to cervical cancer, the fourth most common cancer in the world. In the present study, we investigated the...

    Authors: Parisa Shiri Aghbash, Nima Hemmat, Behzad Baradaran and Hossein Bannazadeh Baghi
    Citation: European Journal of Medical Research 2023 28:42
  5. Ubiquitin and ubiquitin-like (UB/UBL) conjugations are essential post-translational modifications that contribute to cancer onset and advancement. In colon adenocarcinoma (COAD), nonetheless, the biological ro...

    Authors: Liping Liang, Le Liu, Shijie Mai and Ye Chen
    Citation: European Journal of Medical Research 2023 28:41
  6. Peritumoral brain edema (PTBE) is a common complication related to intracranial meningiomas. In several studies, researchers have investigated the pathogenesis of PTBE, and the factors involved in its developm...

    Authors: Hajrullah Ahmeti, Amke Caliebe, Christoph Röcken, Olav Jansen, Maximilian H. Mehdorn and Michael Synowitz
    Citation: European Journal of Medical Research 2023 28:40
  7. Primary central nervous system (CNS) tumors are a heterogeneous group of neoplasms, including benign and malignant tumors. Since there are many heterogeneities in the prevalence reported in previous studies on...

    Authors: Nader Salari, Hooman Ghasemi, Reza Fatahian, Kamran Mansouri, Sadat Dokaneheifard, Mohammad hossain Shiri, Mahvan Hemmati and Masoud Mohammadi
    Citation: European Journal of Medical Research 2023 28:39
  8. Pulmonary vascular abnormalities pose a risk for severe life-threatening hemodynamic disturbances following surgical repair of congenital cardiac communications (CCCs). In the distal lung, small airways and vesse...

    Authors: Kelly C. O. Abud, Clarisse M. Machado, Lucy S. Vilas Boas, Nair Y. Maeda, Eloisa S. Carvalho, Maria Francilene S. Souza, Paula V. Gaiolla, Claudia R. P. Castro, Juliana Pereira, Marlene Rabinovitch and Antonio Augusto Lopes
    Citation: European Journal of Medical Research 2023 28:38
  9. Growth differentiation factor 15 (GDF15) is a stress-inducible factor involved in the inflammatory progression of many complications, including type 2 diabetes mellitus (T2DM). Growing evidence suggests that m...

    Authors: Wen Zhao, Xinwei Li, Xinxin Li, Lu Peng, Yu Li, Yunhui Du, Jianxun He, Yanwen Qin and Huina Zhang
    Citation: European Journal of Medical Research 2023 28:37
  10. To investigate the predictive value of deep learning-based cardiac ultrasound flow imaging for hypertrophic cardiomyopathy (HCM) complicated by arrhythmias.

    Authors: Haotang Wu, Zhiyong Huang, Juanjuan Liu, Jiancheng Dai, Yong Zhao and Weiquan Luo
    Citation: European Journal of Medical Research 2023 28:36
  11. The use of central venous pressure (CVP) measurements among (intensive care unit) ICU patients with severe coma has been questioned. This study aimed to investigate the application value of CVP in this populat...

    Authors: Xin Tong, Xin Feng, Chuanzhi Duan and Aihua Liu
    Citation: European Journal of Medical Research 2023 28:35
  12. Chronic kidney disease (CKD) patients with coronary artery disease (CAD) in the intensive care unit (ICU) have higher in-hospital mortality and poorer prognosis than patients with either single condition. The ...

    Authors: Zixiang Ye, Shuoyan An, Yanxiang Gao, Enmin Xie, Xuecheng Zhao, Ziyu Guo, Yike Li, Nan Shen, Jingyi Ren and Jingang Zheng
    Citation: European Journal of Medical Research 2023 28:33
  13. Microfibrillar-associated protein (MFAP4), initially identified as an extracellular matrix protein, has been demonstrated in multiple human disorders, but it is yet to be discovered following acute coronary sy...

    Authors: Chunming Han, Yuanshu Peng, Xiaoyan Yang, Zongsheng Guo, Xinchun Yang, Pixiong Su, Shubin Guo and Lei Zhao
    Citation: European Journal of Medical Research 2023 28:32
  14. Fib4 index (Fib4) is clinically used as a noninvasive marker of liver fibrosis. In this study, we aimed to preliminarily investigate whether Fib4 can be used to detect individuals who need assessment for alcoh...

    Authors: Hideki Shinoda, Yuya Watanabe, Kota Fukai, Kayoko Kasuya, Yuko Furuya, Shoko Nakazawa, Toru Honda, Takeshi Hayashi, Toru Nakagawa, Masayuki Tatemichi and Masaaki Korenaga
    Citation: European Journal of Medical Research 2023 28:31
  15. People with Parkinson`s disease (PD) often suffer from both motor and cognitive impairments. Simultaneous motor and cognitive training stimulates neurobiological processes which are important especially for pe...

    Authors: Salome Jäggi, Annina Wachter, Manuela Adcock, Eling D. de Bruin, Jens Carsten Möller, Detlef Marks, Raoul Schweinfurther and Eleftheria Giannouli
    Citation: European Journal of Medical Research 2023 28:30
  16. To compare the clinical and angiographic characteristics of high-risk and low-risk spontaneous coronary artery dissection (SCAD) patients to determine the optimal treatment strategy.

    Authors: Yuanji Ma, Xin Zhong, Jiasheng Yin, Hao Lu, Congcong Pan, Dong Huang and Junbo Ge
    Citation: European Journal of Medical Research 2023 28:29
  17. Progestins can suppress endogenous luteinising hormone (LH) secretion from the pituitary gland and have shown similar efficacy in terms of collecting competent oocytes and embryos; however, some inconsistencie...

    Authors: Lu Wang, Jingyun Wang, Yuan Zhang, Chen Qian, Xiaohui Wang, Jie Bai, Fang Li, Zhiqin Chen and Ai Ai
    Citation: European Journal of Medical Research 2023 28:28
  18. Radiotherapy and targeted therapy are essential treatments for patients with brain metastases from human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, the combination of radiothera...

    Authors: Xiaojing Yang, Hanru Ren, Yi Xu, Xue Peng, Wenxi Yu and Zan Shen
    Citation: European Journal of Medical Research 2023 28:27
  19. Aldosterone relieves transcriptional repression of epithelial sodium channel (ENaC) by inhibiting Dot1a and Af9 expression and their interaction with ENaC promoter in various tissues. Expressions of ENaC and A...

    Authors: Shixun Zhong, Biyun Zhang, Li Qin, Qianying Wang and Xiaoli Luo
    Citation: European Journal of Medical Research 2023 28:26
  20. Little is known about the impact of multiple trauma (MT)-related systemic hypoxia on osseous protein concentration of the hypoxia transcriptome. To shed light on this issue, we investigated erythropoietin (Epo...

    Authors: Felix Marius Bläsius, Johannes Greven, Weijun Guo, Eftychios Bolierakis, Zhizhen He, Cavan Lübke, Tim-Philipp Simon, Frank Hildebrand and Klemens Horst
    Citation: European Journal of Medical Research 2023 28:25
  21. The efficacy and safety of epinephrine in patients with out-of-hospital cardiac arrest (OHCA) remains controversial. The meta-analysis was used to comprehensively appraise the influence of epinephrine in OHCA ...

    Authors: Hong Zhong, Zhaohui Yin, Bojin Kou, Pei Shen, Guoli He, Tingting Huang, Jing Liang, Shan Huang, Jiaming Huang, Manhong Zhou and Renli Deng
    Citation: European Journal of Medical Research 2023 28:24
  22. Inherited primary arrhythmias, such as long QT (LQT) syndromes, are electrical abnormalities of the heart mainly due to variants in 3 genes. We herein describe a novel stop-gain pathogenic variant in the KCNQ1 ge...

    Authors: Samira Kalayinia, Mohammad Dalili, Maryam Pourirahim, Majid Maleki and Nejat Mahdieh
    Citation: European Journal of Medical Research 2023 28:23
  23. Healthcare concepts for chronic diseases based on tele-monitoring have become increasingly important during COVID-19 pandemic.

    Authors: Alper Öner, Hermann Dittrich, Fatih Arslan, Sissy Hintz, Jasmin Ortak, Bernard Brandewiede, Miriam Mann, Katja Krockenberger, Alexandre Thiéry, Andreas Ziegler and Christian Schmidt
    Citation: European Journal of Medical Research 2023 28:22
  24. We established 1-h and 1-day survival models after terminal extubation to optimize ventilator use and achieve a balance between critical care for COVID-19 and hospice medicine.

    Authors: Yun-Cong Zheng, Yen-Min Huang, Pin-Yuan Chen, Hsiao-Yean Chiu, Huang-Pin Wu, Chien-Ming Chu, Wei-Siang Chen, Yu-Cheng Kao, Ching-Fang Lai, Ning-Yi Shih and Chien-Hong Lai
    Citation: European Journal of Medical Research 2023 28:21
  25. Currently we do not have an ideal biomarker in lupus nephritis (LN) that should help us to identify those patients with SLE at risk of developing LN or to determine those patients at risk of renal progression....

    Authors: E. Rodríguez-Almaraz, E. Gutiérrez-Solís, E. Rabadán, P. Rodríguez, M. Alonso, L. Carmona, M. J. García de Yébenes, E. Morales and M. Galindo-Izquierdo
    Citation: European Journal of Medical Research 2023 28:19
  26. Generally, the standard surgical route of Morrow begins with the incision of median sternal, which leads to more trauma, pains and discomforts to patients with hypertrophic obstructive cardiomyopathy (HOCM). I...

    Authors: Shuaipeng Zhang, Zhuang Liu, Haiyuan Liu and Chengxin Zhang
    Citation: European Journal of Medical Research 2023 28:18
  27. Numerous studies on myocardial ischemia/reperfusion (MI/R) injury have been undertaken in recent years. Hotspots and developmental trends in MI/R research are being rapidly updated. However, there has been no ...

    Authors: Ming Bai, Jingjing Zhang, De Chen, Mengying Lu, Junfen Li, Zheng Zhang and Xiaowei Niu
    Citation: European Journal of Medical Research 2023 28:17
  28. Orthotopic heart transplantation (HTX) is the gold standard to treat end-stage heart failure. Numerous risk stratification tools have been developed in the past years. However, their clinical utility is limite...

    Authors: René M’Pembele, Sebastian Roth, Anthony Nucaro, Alexandra Stroda, Theresa Tenge, Giovanna Lurati Buse, Florian Bönner, Daniel Scheiber, Christina Ballázs, Igor Tudorache, Hug Aubin, Artur Lichtenberg, Ragnar Huhn and Udo Boeken
    Citation: European Journal of Medical Research 2023 28:16
  29. Iron deficiency (ID) is the most common nutritional disorder worldwide. It is often observed in patients with chronic diseases, such as heart failure (HF), chronic kidney disease (CKD), inflammatory bowel dise...

    Authors: Martina Rohr, Vincent Brandenburg and Hans-Peter Brunner-La Rocca
    Citation: European Journal of Medical Research 2023 28:15
  30. To explore the relationship between blood manganese and liver stiffness in the United States among participants with chronic obstructive pulmonary disease (COPD).

    Authors: Kexing Han, Jiapei Shen, Kexuan Tan, Jiaying Liu, Weijie Sun and Yufeng Gao
    Citation: European Journal of Medical Research 2023 28:14
  31. The burden of the coronavirus disease of 2019 (COVID-19) pandemic on the healthcare sector has been overwhelming, leading to drastic changes in access to healthcare for the public. We aimed to establish the im...

    Authors: Abdel Rahman A. Al manasra, Nadeem B. Alabdallah, Zaid Mesmar, Sami A. Almasarweh, Mohammad Nofal, Osama Shattarah, Qusai Aljarrah, Khalid S. Ibrahim and Doaa Al-qaoud
    Citation: European Journal of Medical Research 2023 28:13
  32. To investigate whether intravenous thrombolysis (IVT) with alteplase (a recombinant tissue plasminogen activator, rt-PA) before endovascular treatment (EVT) is beneficial for acute ischemic stroke (AIS) patien...

    Authors: Xiyang Ji, Bo Song, Hao Zhu, Zhao Jiang, Feng Hua, Sa Wang, Jianbo Zhou, Lin Li, Changfei Dai, Mijuan Zhang, Dong Wei, Lele Zhang, Xiaojie Zhang, Qun Zhang and Ping Chen
    Citation: European Journal of Medical Research 2023 28:12
  33. We used microarrays to analyse the changes in long non-coding RNAs (lncRNAs) and mRNAs in aorta tissue in model rats with lipopolysaccharide-induced sepsis and determined the lncRNA–mRNA and lncRNA–miRNA–mRNA ...

    Authors: Ye-Chen Han, Zhu-Jun Shen, Yi-Ning Wang, Ruo-Lan Xiang and Hong-Zhi Xie
    Citation: European Journal of Medical Research 2023 28:11
  34. Gouty arthritis (GA) is a chronic systemic disease with recurrent acute monoarthritis. In a previous study, a higher incidence of acute flares was observed during the initial marked decrease in serum urate lev...

    Authors: Deng-Ho Yang, Hsiang-Cheng Chen and James Cheng-Chung Wei
    Citation: European Journal of Medical Research 2023 28:10
  35. This study aimed to apply radiomics analysis of the change of deep medullary veins (DMV) on susceptibility-weighted imaging (SWI), and to distinguish mild hypoxic-ischemic encephalopathy (HIE) from moderate-to...

    Authors: Xiamei Zhuang, Huashan Lin, Junwei Li, Yan Yin, Xiao Dong and Ke Jin
    Citation: European Journal of Medical Research 2023 28:9
  36. This study aimed to assess the survival outcomes among patients with out-of-hospital cardiac arrest (CA) who received cardiopulmonary resuscitation (CPR) in China.

    Authors: Guozhong Zhou, Yan Wang, Zihong Sun, Mingqi Yuan, Yunlin Ma, Qianxi Wu, Chunyan Wu, Jing Xu, Yongyi Li, Yunchuan Liu, Zhenzhou Wang and Chao Song
    Citation: European Journal of Medical Research 2023 28:8
  37. Immune indicators are routinely used for the detection of myelodysplastic syndrome (MDS), but these are not utilized as a reference indicator to assess prognosis in MDS-related prognostic evaluation systems, s...

    Authors: Zhaoyun Liu, Xintong Xu, Likun Zheng, Kai Ding, Chun Yang, Jincheng Huang and Rong Fu
    Citation: European Journal of Medical Research 2023 28:7
  38. Oligoasthenospermia (OAT) is the most common cause of male infertility, and the annual incidence of the disease continues to increase due to changing lifestyle habits, increased work pressure and increased env...

    Authors: Zhen Wang, Ziyang Zhou, Lijuan Zhang, Xujie Li, Miaoxiu Li, Yankun Pan, Tiyong Jiao, Xiaoyun Shi, Qing Liu, Congan Wang and Yongquan Wang
    Citation: European Journal of Medical Research 2023 28:6
  39. Cervical lymph node metastasis from unknown primary sites is a challenging clinical issue with a changing therapy model and unpredictable outcomes, which leads to the difficulty in selecting optimal treatments...

    Authors: Mengqian Zhou, Yansheng Wu, Yue Wu, Hong Li, Beibei Ye, Kai Yue, Chao Jing, Yuansheng Duan and Xudong Wang
    Citation: European Journal of Medical Research 2023 28:5
  40. Corona Virus Disease 2019 (COVID-19) presentations range from those similar to the common flu to severe pneumonia resulting in hospitalization with significant morbidity and/or mortality. In this study, we mad...

    Authors: Mohammad Hossein Imanieh, Fatemeh Amirzadehfard, Sina Zoghi, Faezeh Sehatpour, Peyman Jafari, Hamidreza Hassanipour, Maryam Feili, Maryam Mollaie, Pardis Bostanian, Samrad Mehrabi, Reyhaneh Dashtianeh and Afrooz Feili
    Citation: European Journal of Medical Research 2023 28:4
  41. Resistance to different antimicrobial classes by Salmonella species has generated a global public health concern. The spread of extended-spectrum β-lactamases (ESBLs) blaCTX gene variants is also increasing. This...

    Authors: Christopher O. Fakorede, Kehinde O. Amisu, Morteza Saki and Kabiru O. Akinyemi
    Citation: European Journal of Medical Research 2023 28:3
  42. Lipid metabolism has been recently reported to affect the prognosis and tumor immune activity in cancer patients. However, the effect of lipid metabolism on chemosensitivity in patients with breast cancer trea...

    Authors: Wataru Goto, Shinichiro Kashiwagi, Koji Takada, Yuka Asano, Kana Ogisawa, Tamami Morisaki, Masatsune Shibutani, Hiroaki Tanaka and Kiyoshi Maeda
    Citation: European Journal of Medical Research 2023 28:2
  43. The implantation of carotid artery stents prevents recurrent ischemic stroke in patients with carotid stenosis. This study aimed to investigate associations between change of ophthalmic artery flow (COAF) post...

    Authors: Hui-Yi Yang, Ie-Bin Lian, Shih-Chun Wang, Ta-Tsung Lin, Yang-Hao Ou, Chi-Kuang Liu and Chih-Ming Lin
    Citation: European Journal of Medical Research 2023 28:1
  44. Breast cancer (BC) is a highly malignant and heterogeneous tumor which is currently the cancer with the highest incidence and seriously endangers the survival and prognosis of patients. Aging, as a research ho...

    Authors: Zitao Wang, Hua Liu, Yiping Gong and Yanxiang Cheng
    Citation: European Journal of Medical Research 2022 27:317
  45. The purpose of this study was to evaluate the effectiveness of sequential correction using satellite rod in patients with severe rigid spinal deformity undergoing posterior-only PVCR.

    Authors: Huipeng Yin, Kun Wang, Shuai Li, Yu Song, Xiaobo Feng, Wenbin Hua, Xinghuo Wu, Yukun Zhang and Cao Yang
    Citation: European Journal of Medical Research 2022 27:316
  46. The objective of this study was to report and discuss clinical analysis, including the diagnosis and treatment of 4 cases of neuromyelitis optica spectrum disease (NMOSD) with area postrema syndrome (APS) as t...

    Authors: Ting Liu, Lijuan Li, Xiaopeng Guo, Qifu Li, Dandan Jia and Lin Ma
    Citation: European Journal of Medical Research 2022 27:315
  47. Heart failure with mildly reduced ejection fraction (HFmrEF)  or  heart failure with preserved ejection fraction (HFpEF)  are associated with significant morbidity and mortality, as well as growing health and ...

    Authors: Yintang Wang, Tong Gao, Chang Meng, Siyuan Li, Lei Bi, Yu Geng and Ping Zhang
    Citation: European Journal of Medical Research 2022 27:314
  48. Chronic subdural hematoma (CSDH) is a common disease that forms between the dura and arachnoid membranes of the brain. With the development of medications and surgery, significant progress has been made in the...

    Authors: Rundong Chen, Yanpeng Wei, Xiaolong Xu, Renkun Zhang, Yuhao Tan, Guanghao Zhang, Hongwei Yin, Dongwei Dai, Qiang Li, Rui Zhao, Qinghai Huang, Yi Xu, Pengfei Yang, Jianmin Liu and Qiao Zuo
    Citation: European Journal of Medical Research 2022 27:309

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